1-[2-[2-hydroxy-3-(4-methylpiperazin-1-yl)propoxy]phenyl]ethanone,dihydrochloride

MOLECULAR FORMULA :

C16-H24-N2-O3.2Cl-H

MOLECULAR WEIGHT :

365.34

WISWESSER LINE NOTATION :

T6N DNTJ A1YQ1OR BV1& D1 &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

240 mg/kg

TOXIC EFFECTS :

Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Behavioral - excitement

REFERENCE :

JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 16,797,1973