8-chloro-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid

Modify Date: 2024-01-12 11:13:21

8-chloro-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid Structure
8-chloro-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid structure
Common Name 8-chloro-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid
CAS Number 641993-18-2 Molecular Weight 291.611
Density 1.6±0.1 g/cm3 Boiling Point 391.4±42.0 °C at 760 mmHg
Molecular Formula C11H5ClF3NO3 Melting Point N/A
MSDS N/A Flash Point 190.5±27.9 °C

 Names

Name 8-chloro-4-oxo-5-(trifluoromethyl)-1H-quinoline-3-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 391.4±42.0 °C at 760 mmHg
Molecular Formula C11H5ClF3NO3
Molecular Weight 291.611
Flash Point 190.5±27.9 °C
Exact Mass 290.990997
PSA 70.16000
LogP 4.21
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.560

 Synthetic Route

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8-chloro-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid Structure

8-chloro-4-oxo-...

CAS#:641993-18-2

Literature: VERTEX PHARMACEUTICALS INCORPORATED; ZHANG, Beili; KRAWIEC, Mariusz; LUISI, Brian; MEDEK, Ales Patent: WO2011/50220 A1, 2011 ; Location in patent: Page/Page column 44-45 ; WO 2011/050220 A1

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8-chloro-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid Structure

8-chloro-4-oxo-...

CAS#:641993-18-2

Literature: VERTEX PHARMACEUTICALS INCORPORATED; ZHANG, Beili; KRAWIEC, Mariusz; LUISI, Brian; MEDEK, Ales Patent: WO2011/50220 A1, 2011 ; WO 2011/050220 A1

~%

8-chloro-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid Structure

8-chloro-4-oxo-...

CAS#:641993-18-2

Literature: VERTEX PHARMACEUTICALS INCORPORATED; ZHANG, Beili; KRAWIEC, Mariusz; LUISI, Brian; MEDEK, Ales Patent: WO2011/50220 A1, 2011 ; WO 2011/050220 A1

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

8-Chloro-4-oxo-5-(trifluoromethyl)-1,4-dihydro-3-quinolinecarboxylic acid
8-chloro-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid
QC-4930
3-Quinolinecarboxylic acid, 8-chloro-1,4-dihydro-4-oxo-5-(trifluoromethyl)-