aminometradine

Modify Date: 2024-01-03 16:53:22

aminometradine Structure
aminometradine structure
Common Name aminometradine
CAS Number 642-44-4 Molecular Weight 195.21800
Density 1.167g/cm3 Boiling Point 292.8ºC at 760 mmHg
Molecular Formula C9H13N3O2 Melting Point N/A
MSDS N/A Flash Point 130.9ºC

 Names

Name 6-amino-3-ethyl-1-prop-2-enylpyrimidine-2,4-dione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.167g/cm3
Boiling Point 292.8ºC at 760 mmHg
Molecular Formula C9H13N3O2
Molecular Weight 195.21800
Flash Point 130.9ºC
Exact Mass 195.10100
PSA 70.02000
LogP 0.37930
Index of Refraction 1.534

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YQ8665000
CHEMICAL NAME :
Uracil, 1-allyl-6-amino-3-ethyl-
CAS REGISTRY NUMBER :
642-44-4
BEILSTEIN REFERENCE NO. :
0175533
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C9-H13-N3-O2
MOLECULAR WEIGHT :
195.25
WISWESSER LINE NOTATION :
T6NVNVJ A2U1 C2 FZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 14,392,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PRPHA8 Produits Pharmaceutiques. (Paris, France) V.1-16, 1946-61. For publisher information, see PPRPAS. Volume(issue)/page/year: 13,125,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
560 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PRPHA8 Produits Pharmaceutiques. (Paris, France) V.1-16, 1946-61. For publisher information, see PPRPAS. Volume(issue)/page/year: 13,125,1958

 Synthetic Route

~%

aminometradine Structure

aminometradine

CAS#:642-44-4

Literature: Papesch; Schroeder Journal of Organic Chemistry, 1951 , vol. 16, p. 1879,1881,1887

~%

aminometradine Structure

aminometradine

CAS#:642-44-4

Literature: Papesch; Schroeder Journal of Organic Chemistry, 1951 , vol. 16, p. 1879,1881,1887

~%

aminometradine Structure

aminometradine

CAS#:642-44-4

Literature: Papesch; Schroeder Journal of Organic Chemistry, 1951 , vol. 16, p. 1879,1881,1887

 Synonyms

Aminometramide
Catapyrin
1-Allyl-6-amino-3-ethyl-2,4(1H,3H)-pyrimidinedione
Alacil
Aminometradinum [INN-Latin]
1-allyl-3-ethyl-6-aminouracil
6-amino-3-ethyl-1-(2-propenyl)-2,4(1H,3H)-pyrimidinedione
Mincard
3-ethyl-1-allyl-6-amino-1H-pyrimidine-2,4-dione
Mictine
AMINOMETRADINE
1-allyl-6-amino-3-ethyluracil
Allacyl
Katapyrin
3-Aethyl-1-allyl-6-amino-1H-pyrimidin-2,4-dion
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