aminometradine

Modify Date: 2025-08-25 12:04:09

aminometradine Structure
aminometradine structure
Common Name aminometradine
CAS Number 642-44-4 Molecular Weight 195.21800
Density 1.167g/cm3 Boiling Point 292.8ºC at 760 mmHg
Molecular Formula C9H13N3O2 Melting Point N/A
MSDS N/A Flash Point 130.9ºC

 Names

Name 6-amino-3-ethyl-1-prop-2-enylpyrimidine-2,4-dione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.167g/cm3
Boiling Point 292.8ºC at 760 mmHg
Molecular Formula C9H13N3O2
Molecular Weight 195.21800
Flash Point 130.9ºC
Exact Mass 195.10100
PSA 70.02000
LogP 0.37930
Index of Refraction 1.534
InChIKey NGXUUAFYUCOICP-UHFFFAOYSA-N
SMILES C=CCn1c(N)cc(=O)n(CC)c1=O

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YQ8665000
CHEMICAL NAME :
Uracil, 1-allyl-6-amino-3-ethyl-
CAS REGISTRY NUMBER :
642-44-4
BEILSTEIN REFERENCE NO. :
0175533
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C9-H13-N3-O2
MOLECULAR WEIGHT :
195.25
WISWESSER LINE NOTATION :
T6NVNVJ A2U1 C2 FZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 14,392,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PRPHA8 Produits Pharmaceutiques. (Paris, France) V.1-16, 1946-61. For publisher information, see PPRPAS. Volume(issue)/page/year: 13,125,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
560 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PRPHA8 Produits Pharmaceutiques. (Paris, France) V.1-16, 1946-61. For publisher information, see PPRPAS. Volume(issue)/page/year: 13,125,1958

 Synthetic Route

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aminometradine Structure

aminometradine

CAS#:642-44-4

Literature: Papesch; Schroeder Journal of Organic Chemistry, 1951 , vol. 16, p. 1879,1881,1887

~%

aminometradine Structure

aminometradine

CAS#:642-44-4

Literature: Papesch; Schroeder Journal of Organic Chemistry, 1951 , vol. 16, p. 1879,1881,1887

~%

aminometradine Structure

aminometradine

CAS#:642-44-4

Literature: Papesch; Schroeder Journal of Organic Chemistry, 1951 , vol. 16, p. 1879,1881,1887

 aminometradineBioassay

View more

Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: ULK1_INH_LUMI_1536_1X%INH PRUN
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 Synonyms

Aminometramide
Catapyrin
1-Allyl-6-amino-3-ethyl-2,4(1H,3H)-pyrimidinedione
Alacil
Aminometradinum [INN-Latin]
1-allyl-3-ethyl-6-aminouracil
6-amino-3-ethyl-1-(2-propenyl)-2,4(1H,3H)-pyrimidinedione
Mincard
3-ethyl-1-allyl-6-amino-1H-pyrimidine-2,4-dione
Mictine
AMINOMETRADINE
1-allyl-6-amino-3-ethyluracil
Allacyl
Katapyrin
3-Aethyl-1-allyl-6-amino-1H-pyrimidin-2,4-dion
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