sodium folate
Modify Date: 2026-07-02 11:27:59
sodium folate structure
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Common Name | sodium folate | ||
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| CAS Number | 6484-89-5 | Molecular Weight | 463.37900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H18N7NaO6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of sodium folateFolic acid (Vitamin B9) sodium is a orally active essential nutrient from the B complex group of vitamins. Folic acid sodium shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid sodium can be used to the treatment of megaloblastic and macrocytic anemias due to folic deficiency[1][2][3][4]. |
| Name | sodium folate |
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| Description | Folic acid (Vitamin B9) sodium is a orally active essential nutrient from the B complex group of vitamins. Folic acid sodium shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid sodium can be used to the treatment of megaloblastic and macrocytic anemias due to folic deficiency[1][2][3][4]. |
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| Related Catalog | |
| Target |
Microbial Metabolite |
| In Vitro | Folic acid sodium plays a critical role in the prevention of chromosome breakage and hypomethylation of DNA[1]. |
| In Vivo | Folic acid sodium (10, 50, 100 mg/kg; p.o.) shows an antidepressant-like effect in thisbehavioral mouse model[2]. Folic acid sodium (1, 10 nmol/site) shows no psychostimulant effect in mice habituated to the novel environment[2]. Folic acid sodium (1, 5 mg/kg; p.o.) prevents epigenetic modification of hepatic gene expression in the offspring in rats[3]. Animal Model: 30-40 g swiss mice[2] Dosage: 10, 50, 100 mg/kg Administration: P.o. Result: Decreased the immobility time in the forced swimming test (FST) (F324=11.21) and produced a significant effect in the immobility time in the tail suspension test (TST) (F3,20=5.71). Animal Model: 30-40 g swiss mice[2] Dosage: 1-10 nmol/site Administration: I.c.v. Result: Decreased the immobility time of mice in the FST (F3,22=12.31) and TST (F3,22=5.50). Animal Model: Virgin female Wistar rats[3] Dosage: 1, 5 mg/kg (180 g/kg protein with 1 mg/kg folic acid or 90 g/kg casein with 1, 5 mg/kg folic acid) Administration: P.o. Result: Prevented epigenetic modification of hepatic gene expression in the offspring. |
| References |
| Molecular Formula | C19H18N7NaO6 |
|---|---|
| Molecular Weight | 463.37900 |
| Exact Mass | 463.12200 |
| PSA | 216.11000 |
| InChIKey | ZTYOEHTVHXWFJT-YDALLXLXSA-M |
| SMILES | Nc1nc2ncc(CNc3ccc(C(=O)NC(CCC(=O)O)C(=O)[O-])cc3)nc2c(=O)[nH]1.[Na+] |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
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Name: Inhibition of Escherichia coli MurD assessed as residual activity at 500 uM
Source: ChEMBL
Target: N/A
External Id: CHEMBL1010837
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Name: Increase the activity of the Burkholderia fixLJ 2-component system
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Burkholderia multivorans
External Id: HMS1625
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Drug activation in human Hep3B cells assessed as human CYP2C9-mediated drug metabolis...
Source: ChEMBL
Target: Cytochrome P450 2C9
External Id: CHEMBL4478999
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Name: Drug activation in human Hep3B cells assessed as human CYP3A4-mediated drug metabolis...
Source: ChEMBL
Target: Cytochrome P450 3A4
External Id: CHEMBL4479000
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Name: It is the ratio of apparent kinetic constant to that of relative maximum velocity
Source: ChEMBL
Target: N/A
External Id: CHEMBL848231
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Name: Dual reporter qHTS for antagonist of Pregnane X Receptor (hPXR) against the NCATS DSH...
Source: NCGC
External Id: DSHEA-v1-PXR-antagonist-CTF
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