N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2-piperidin-4-yl-1,3-thiazol-4-yl)methyl]oxy}quinazolin-4-amine

Modify Date: 2025-08-20 19:24:15

N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2-piperidin-4-yl-1,3-thiazol-4-yl)methyl]oxy}quinazolin-4-amine Structure
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2-piperidin-4-yl-1,3-thiazol-4-yl)methyl]oxy}quinazolin-4-amine structure
Common Name N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2-piperidin-4-yl-1,3-thiazol-4-yl)methyl]oxy}quinazolin-4-amine
CAS Number 650579-84-3 Molecular Weight 516.4
Density N/A Boiling Point N/A
Molecular Formula C24H23Cl2N5O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2-piperidin-4-yl-1,3-thiazol-4-yl)methyl]oxy}quinazolin-4-amine

 Chemical & Physical Properties

Molecular Formula C24H23Cl2N5O2S
Molecular Weight 516.4
InChIKey NYIGUQNAOHAUFR-UHFFFAOYSA-N
SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(C2CCNCC2)n1

 Bioassay

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Name: AlphaScreen Assay from US Patent US9796704: "Substituted quinazolines as receptor-typ...
Source: BindingDB
Target: N/A
External Id: BindingDB_2046_1
Name: Inhibition of recombinant human N-terminal GST His6-tagged thrombin cleavage site-fus...
Source: ChEMBL
Target: Epidermal growth factor receptor
External Id: CHEMBL3883067
Name: Inhibition of recombinant human N-terminal GST His6-tagged thrombin cleavage site-fus...
Source: ChEMBL
Target: Receptor tyrosine-protein kinase erbB-2
External Id: CHEMBL3883068
Name: Inhibition of recombinant human N-terminal GST-fused KDR (D807 to V1356 residues) exp...
Source: ChEMBL
Target: Vascular endothelial growth factor receptor 2
External Id: CHEMBL3883069
Name: Inhibition of recombinant human N-terminal His6-tagged EphA2 (N598 to R890 residues) ...
Source: ChEMBL
Target: Ephrin type-A receptor 2
External Id: CHEMBL3883065
Name: Inhibition of recombinant human N-terminal His6-tagged EphB4 kinase domain (E605 to E...
Source: ChEMBL
Target: Ephrin type-B receptor 4
External Id: CHEMBL3883066
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