Bestatin methyl ester

Modify Date: 2026-07-30 20:11:05

Bestatin methyl ester Structure
Bestatin methyl ester structure
Common Name Bestatin methyl ester
CAS Number 65322-89-6 Molecular Weight 322.39900
Density N/A Boiling Point N/A
Molecular Formula C17H26N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name methyl (2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoate
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C17H26N2O4
Molecular Weight 322.39900
Exact Mass 322.18900
PSA 105.14000
LogP 2.16180
InChIKey WGNKTWBIPBOGLO-ILXRZTDVSA-N
SMILES COC(=O)C(CC(C)C)NC(=O)C(O)C(N)Cc1ccccc1

 Precursor & DownStream

Precursor  0

DownStream  1

 Bestatin methyl esterBioassay

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Name: Enhancement of etoposide-induced apoptosis of human HT1080 cells at 10 uM
Source: ChEMBL
Target: HT-1080
External Id: CHEMBL984310
Name: Enhancement of cisplatin-induced apoptosis of human HT1080 cells at 10 uM
Source: ChEMBL
Target: HT-1080
External Id: CHEMBL984309
Name: Enhancement of camptothecin-induced apoptosis of human HT1080 cells at 10 uM
Source: ChEMBL
Target: HT-1080
External Id: CHEMBL984311
Name: Promotion of flag-tagged cIAP1 degradation in human HT1080 cells assessed as decrease...
Source: ChEMBL
Target: Baculoviral IAP repeat-containing protein 2
External Id: CHEMBL984306
Name: Enhancement of anti-Fas antibody CH11-induced apoptosis of human HT1080 cells at 30 u...
Source: ChEMBL
Target: HT-1080
External Id: CHEMBL984305
Name: Enhancement of actinomycin D-induced apoptosis of human HT1080 cells at 10 uM
Source: ChEMBL
Target: HT-1080
External Id: CHEMBL984308
Name: Inhibition of flag-tagged cIAP1 production in human HT1080 cells assessed as ubiquiti...
Source: ChEMBL
Target: Baculoviral IAP repeat-containing protein 2
External Id: CHEMBL984307
Name: Displacement of DanBE from to GST-tagged cIAP1 BIR3 domain after 5 mins by Fluorescen...
Source: ChEMBL
Target: Baculoviral IAP repeat-containing protein 2
External Id: CHEMBL2182125
Name: Inhibition of BCR-ABL signaling pathway in human K562 cells assessed as suppression o...
Source: ChEMBL
Target: Breakpoint cluster region protein
External Id: CHEMBL3861456
Name: Inhibition of BCR-ABL phosphorylation in human K562 cells at 100 uM after 8 hrs in pr...
Source: ChEMBL
Target: Breakpoint cluster region protein
External Id: CHEMBL3861457
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 Synonyms

Methyl Bestatin
Bestatin Methyl Ester
(-)-N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine Methyl Ester
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