Morazone

Modify Date: 2025-09-27 13:46:11

Morazone Structure
Morazone structure
Common Name Morazone
CAS Number 6536-18-1 Molecular Weight 377.47900
Density 1.153g/cm3 Boiling Point 503.9ºC at 760 mmHg
Molecular Formula C23H27N3O2 Melting Point N/A
MSDS N/A Flash Point 258.5ºC

 Use of Morazone


Morazone is a nonsteroidal anti-inflammatory drug which is used as an analgesic. It produces phenmetrazine as a major metabolite and has been reported to have been abused as a recreational drug in the past.

 Names

Name 1,5-dimethyl-4-[(3-methyl-2-phenylmorpholin-4-yl)methyl]-2-phenylpyrazol-3-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.153g/cm3
Boiling Point 503.9ºC at 760 mmHg
Molecular Formula C23H27N3O2
Molecular Weight 377.47900
Flash Point 258.5ºC
Exact Mass 377.21000
PSA 39.40000
LogP 3.38430
Index of Refraction 1.587
InChIKey OOGNFQMTGRZRAB-UHFFFAOYSA-N
SMILES Cc1c(CN2CCOC(c3ccccc3)C2C)c(=O)n(-c2ccccc2)n1C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ9200000
CHEMICAL NAME :
3-Pyrazolin-5-one, 2,3-dimethyl-4-(3-methyl-2-phenylmorpholino)methyl-1- phenyl-
CAS REGISTRY NUMBER :
6536-18-1
BEILSTEIN REFERENCE NO. :
0347917
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C23-H27-N3-O2
MOLECULAR WEIGHT :
377.53
WISWESSER LINE NOTATION :
T6N DOTJ B1 CR& A1- DT5NNVJ A1 BR E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 5,346,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 5,346,1965

 Synthetic Route

~%

Morazone Structure

Morazone

CAS#:6536-18-1

Literature: Hengen et al. Arzneimittel Forschung, 1958 , vol. 8, p. 421

 Synonyms

1,5-dimethyl-4-(3-methyl-2-phenyl-morpholinomethyl)-2-phenyl-1,2-dihydro-pyrazol-3-one
1,5-Dimethyl-4-(3-methyl-2-phenyl-morpholinomethyl)-2-phenyl-1,2-dihydro-pyrazol-3-on
Morazonum [INN-Latin]
R 445
EINECS 229-447-1
Morazone
1,5-dimethyl-4-(3-methyl-2-phenyl-morpholin-4-ylmethyl)-2-phenyl-1,2-dihydro-pyrazol-3-one
Tarugan
Novartrina
Morazona [INN-Spanish]
Orsimon
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