2-(4-methoxyphenyl)-3-phenyl-1,3-thiazolidin-4-one

Modify Date: 2026-08-03 11:13:00

2-(4-methoxyphenyl)-3-phenyl-1,3-thiazolidin-4-one Structure
2-(4-methoxyphenyl)-3-phenyl-1,3-thiazolidin-4-one structure
Common Name 2-(4-methoxyphenyl)-3-phenyl-1,3-thiazolidin-4-one
CAS Number 65655-83-6 Molecular Weight 285.36100
Density N/A Boiling Point N/A
Molecular Formula C16H15NO2S Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 2-(4-methoxyphenyl)-3-phenyl-1,3-thiazolidin-4-one
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C16H15NO2S
Molecular Weight 285.36100
Exact Mass 285.08200
PSA 54.84000
LogP 3.53880
InChIKey NHKLTJRRDBPZND-UHFFFAOYSA-N
SMILES COc1ccc(C2SCC(=O)N2c2ccccc2)cc1

 Synthetic Route

~71%

2-(4-methoxyphenyl)-3-phenyl-1,3-thiazolidin-4-one Structure

2-(4-methoxyphe...

CAS#:65655-83-6

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Literature: Kumar, Dinesh; Sonawane, Mukesh; Pujala, Brahmam; Jain, Varun K.; Bhagat, Srikant; Chakraborti, Asit K. Green Chemistry, 2013 , vol. 15, # 10 p. 2872 - 2884

~66%

2-(4-methoxyphenyl)-3-phenyl-1,3-thiazolidin-4-one Structure

2-(4-methoxyphe...

CAS#:65655-83-6

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Literature: Elbannany; Azim Hady Ibrahim Pharmazie, 1986 , vol. 41, # 2 p. 144 - 145

~%

2-(4-methoxyphenyl)-3-phenyl-1,3-thiazolidin-4-one Structure

2-(4-methoxyphe...

CAS#:65655-83-6

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Literature: Satsumabayashi,S. et al. Synthesis, 1977 , p. 881 - 883

~%

2-(4-methoxyphenyl)-3-phenyl-1,3-thiazolidin-4-one Structure

2-(4-methoxyphe...

CAS#:65655-83-6

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Literature: Tierney, John Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 997 - 1001

 Bioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Antitubercular activity against dormant Mycobacterium tuberculosis H37Ra assessed as ...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL3784685
Name: Antitubercular activity against dormant Mycobacterium bovis BCG ATCC 35743 assessed a...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3784684
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: Antitubercular activity against dormant Mycobacterium bovis BCG ATCC 35743 assessed a...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3784683
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Antitubercular activity against dormant Mycobacterium bovis BCG ATCC 35743 by NR assa...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3784689
Name: Antitubercular activity against dormant Mycobacterium bovis BCG ATCC 35743 assessed a...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3784688
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 Synonyms

2-(4-Methoxyphenyl)-4-oxo-3-phenyltetrahydrothiazol
2-(4-methoxy-phenyl)-3-phenyl-thiazolidin-4-one
HMS2867D21
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