Ac-Lys(Ac)-D-Ala-D-lactic acid

Modify Date: 2024-01-12 18:03:46

Ac-Lys(Ac)-D-Ala-D-lactic acid Structure
Ac-Lys(Ac)-D-Ala-D-lactic acid structure
Common Name Ac-Lys(Ac)-D-Ala-D-lactic acid
CAS Number 65882-12-4 Molecular Weight 373.401
Density 1.2±0.1 g/cm3 Boiling Point 740.5±60.0 °C at 760 mmHg
Molecular Formula C16H27N3O7 Melting Point N/A
MSDS N/A Flash Point 401.7±32.9 °C

 Use of Ac-Lys(Ac)-D-Ala-D-lactic acid


Ac-Lys(Ac)-D-Ala-D-Lactic acid is a depsipeptide substrate for penicillin-sensitive D-alanine carboxypeptidases (DD-carboxypeptidases)[1].

 Names

Name 2-[2-(2,6-diacetamidohexanoylamino)propanoyloxy]propanoic acid
Synonym More Synonyms

 Ac-Lys(Ac)-D-Ala-D-lactic acid Biological Activity

Description Ac-Lys(Ac)-D-Ala-D-Lactic acid is a depsipeptide substrate for penicillin-sensitive D-alanine carboxypeptidases (DD-carboxypeptidases)[1].
Related Catalog
References

[1]. Rasmussen JR, et al. Utilization of a depsipeptide substrate for trapping acyl-enzyme intermediates of penicillin-sensitive D-alanine carboxypeptidases. Proc Natl Acad Sci U S A. 1978 Jan;75(1):84-8.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 740.5±60.0 °C at 760 mmHg
Molecular Formula C16H27N3O7
Molecular Weight 373.401
Flash Point 401.7±32.9 °C
Exact Mass 373.184906
PSA 150.90000
LogP -1.02
Vapour Pressure 0.0±5.3 mmHg at 25°C
Index of Refraction 1.495

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
HS Code 2924199090

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles1

More Articles
Mechanism of penicillin action: penicillin and substrate bind covalently to the same active site serine in two bacterial D-alanine carboxypeptidases.

Proc. Natl. Acad. Sci. U. S. A. 76 , 2730, (1979)

It has been hypothesized that penicillin acts as a structural analog of the acyl-D-alanyl-D-alanine terminus of nascent bacterial cell wall and that it consequently binds to and acylates the active si...

 Synonyms

Nalpha,Nepsilon-Diacetyl-Lys-D-Ala-D-lactic acid
N|A,N|A-Diacetyl-Lys-D-Ala-D-lactic acid
(1R)-1-Carboxyethyl N,N-diacetyl-L-lysyl-D-alaninate
D-Alanine, N,N-diacetyl-L-lysyl-, (1R)-1-carboxyethyl ester
AC-LYS(AC)-D-ALA-D-LACTIC ACID