Protectin D1

Modify Date: 2024-01-06 12:49:36

Protectin D1 Structure
Protectin D1 structure
Common Name Protectin D1
CAS Number 660430-03-5 Molecular Weight 360.48700
Density N/A Boiling Point N/A
Molecular Formula C22H32O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Protectin D1


Protectin D1, neuroprotectin D1 when generated by neural cells, is a member of a new family of bioactive products generated from docosahexaenoic acid. Protectin D1 is also a specialized pro-resolving mediator with potent pro-resolving and anti-inflammatory effects in vivo in several human disease models[1][2].

 Names

Name protectin D1
Synonym More Synonyms

 Protectin D1 Biological Activity

Description Protectin D1, neuroprotectin D1 when generated by neural cells, is a member of a new family of bioactive products generated from docosahexaenoic acid. Protectin D1 is also a specialized pro-resolving mediator with potent pro-resolving and anti-inflammatory effects in vivo in several human disease models[1][2].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Tungen JE, et al. Synthesis of protectin D1 analogs: novel pro-resolution and radiotracer agents. Org Biomol Chem. 2018;16(36):6818-6823.

[2]. Serhan CN, et al. Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes [published correction appears in J Immunol. 2006 Mar 15;176(6):3843]. J Immunol. 2006;176(3):1848-1859.

 Chemical & Physical Properties

Molecular Formula C22H32O4
Molecular Weight 360.48700
Exact Mass 360.23000
PSA 77.76000
LogP 4.49050

 Synonyms

(4Z,7Z,10R,11E,13E,15Z,17S,19Z)-10,17-dihydroxy-4,7,11,13,15,19-docosahexaenoic acid
10R,17S-dihydroxydocosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid
10R,17S-dihydroxy-docosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid
NPD1
PD1
neuroprotectin D1