NCGC00379308

Modify Date: 2024-01-02 10:05:47

NCGC00379308 Structure
NCGC00379308 structure
Common Name NCGC00379308
CAS Number 662164-09-2 Molecular Weight 333.43
Density N/A Boiling Point N/A
Molecular Formula C20H23N5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NCGC00379308


D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 by direct TSHR activation and potentiates TSH-mediated preosteoblast differentiation in vitro[1].

 Names

Name D3-βArr

 NCGC00379308 Biological Activity

Description D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 by direct TSHR activation and potentiates TSH-mediated preosteoblast differentiation in vitro[1].
Related Catalog
Target

Thyrotropin receptor (TSHR)[1]

References

[1]. Neumann S, et al. Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro. J Pharmacol Exp Ther. 2018 Jan;364(1):38-45.

 Chemical & Physical Properties

Molecular Formula C20H23N5
Molecular Weight 333.43
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