alpha-Cyano-1-piperidineacrylic acid ethyl ester

Modify Date: 2024-01-19 21:05:21

alpha-Cyano-1-piperidineacrylic acid ethyl ester Structure
alpha-Cyano-1-piperidineacrylic acid ethyl ester structure
Common Name alpha-Cyano-1-piperidineacrylic acid ethyl ester
CAS Number 6630-63-3 Molecular Weight 208.25700
Density 1.159g/cm3 Boiling Point 317.8ºC at 760 mmHg
Molecular Formula C11H16N2O2 Melting Point N/A
MSDS N/A Flash Point 146ºC

 Names

Name ethyl (Z)-2-cyano-3-piperidin-1-ylprop-2-enoate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.159g/cm3
Boiling Point 317.8ºC at 760 mmHg
Molecular Formula C11H16N2O2
Molecular Weight 208.25700
Flash Point 146ºC
Exact Mass 208.12100
PSA 53.33000
LogP 1.38078
Index of Refraction 1.556

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TM4021000
CHEMICAL NAME :
1-Piperidineacrylic acid, alpha-cyano-, ethyl ester
CAS REGISTRY NUMBER :
6630-63-3
LAST UPDATED :
198909
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H16-N2-O2
MOLECULAR WEIGHT :
208.29
WISWESSER LINE NOTATION :
T6NTJ A1UYCN&VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 7,68,1964

 Synthetic Route

~71%

alpha-Cyano-1-piperidineacrylic acid ethyl ester Structure

alpha-Cyano-1-p...

CAS#:6630-63-3

Literature: Darwisha, Elham S.; Abdelrahmana, Mahmoud A.; Salaheldin, Abdellatif M. Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2011 , vol. 66, # 6 p. 597 - 602

 Synonyms

Piperidinomethylen-cyanessigsaeureaethylester
2-cyano-3-piperidin-1-yl-acrylic acid ethyl ester
1H-Pyrrole-2-carbonitrile,3-phenyl
2-Cyano-3-phenyl-pyrrol
3-Piperidino-2-cyan-acrylsaeureaethylester
3-phenyl-pyrrole-2-carbonitrile
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