rac-AZD 6482
Modify Date: 2025-09-18 13:53:02
rac-AZD 6482 structure
|
Common Name | rac-AZD 6482 | ||
|---|---|---|---|---|
| CAS Number | 663620-70-0 | Molecular Weight | 408.45000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H24N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of rac-AZD 6482rac-AZD 6482 (rac-KIN-193) is a less active racemate of AZD 6482. AZD 6482 is a potent and selective p110β inhibitor with an IC50 of 0.69 nM. |
| Name | 2-({1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin -9-yl]ethyl}amino)benzoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | rac-AZD 6482 (rac-KIN-193) is a less active racemate of AZD 6482. AZD 6482 is a potent and selective p110β inhibitor with an IC50 of 0.69 nM. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C22H24N4O4 |
|---|---|
| Molecular Weight | 408.45000 |
| Exact Mass | 408.18000 |
| PSA | 96.17000 |
| LogP | 2.84880 |
| InChIKey | IRTDIKMSKMREGO-UHFFFAOYSA-N |
| SMILES | Cc1cc(C(C)Nc2ccccc2C(=O)O)c2nc(N3CCOCC3)cc(=O)n2c1 |
|
~67%
rac-AZD 6482 CAS#:663620-70-0 |
| Literature: Fjellstrom, Ola; Gustafsson, David; Lindberg, Jan A.; Jackson, Shaun Patent: US2009/191177 A1, 2009 ; Location in patent: Page/Page column 7 ; US 20090191177 A1 |
![9-(1-Hydroxyethyl)-7-methyl-2-(morpholin-4-yl)-4H-pyrido[1,2-a]pyrimidin-4-one structure](https://image.chemsrc.com/caspic/405/1173900-35-0.png)
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| (+/-)-1-tert-Butyldimethylsilyloxy-3-vinylcyclohex-2-ene |
| 2-{[1-(7-methyl-2-morpholin-4-yl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethyl]amino}benzoic acid |
| 3-<(tert-Butyldimethylsilyl)oxy>-1-vinylcyclohexene |
| Silane,(1,1-dimethylethyl)[(3-ethenyl-2-cyclohexen-1-yl)oxy]dimethyl |
| (+/-)-2-({1-[7-methyl-2-(morpholin-4-yl)-4-oxo-pyrido[1,2-a]pyrimidin-9-yl]ethyl}amino)benzoic acid |
| 3-(tert-butyldimethylsiloxy)-1-vinyl-1-cyclohexene |