Colchicine, N-deacetyl-10-demethoxy-N-(beta-d-glucopyranosyl)-10-(methylthio)-

Modify Date: 2024-02-18 18:51:29

Colchicine, N-deacetyl-10-demethoxy-N-(beta-d-glucopyranosyl)-10-(methylthio)- structure	Common Name	Colchicine, N-deacetyl-10-demethoxy-N-(beta-d-glucopyranosyl)-10-(methylthio)-
	CAS Number	66568-82-9	Molecular Weight	535.60700
	Density	1.43g/cm3	Boiling Point	839.8ºC at 760 mmHg
	Molecular Formula	C₂₆H₃₃NO₉S	Melting Point	N/A
	MSDS	N/A	Flash Point	461.7ºC

Name	Benzo[a]heptalen-9(5H)-one, 7-(.β.-D-glucopyranosylamino)-6,7-dihydro-1,2,3-trimethoxy-10-(methylthio)-, (S)

Density	1.43g/cm3
Boiling Point	839.8ºC at 760 mmHg
Molecular Formula	C₂₆H₃₃NO₉S
Molecular Weight	535.60700
Flash Point	461.7ºC
Exact Mass	535.18800
PSA	172.24000
LogP	1.22920
Index of Refraction	1.656

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DF9488000

CHEMICAL NAME :: Benzo(a)heptalen-9(5H)-one, 7-(beta-D-glucopyranosylamino)-6,7-dihydro-1,2,3-trim ethoxy-10- (methylthio)-, (S)-

CAS REGISTRY NUMBER :: 66568-82-9

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C26-H33-N-O9-S

MOLECULAR WEIGHT :: 535.66

WISWESSER LINE NOTATION :: L B677 MV&T&J CO1 DO1 EO1 NS1 JM- BT6OTJ CQ DQ EQ F1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 104 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,636,1981