5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid

Modify Date: 2024-01-09 10:21:55

5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Structure
5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid structure
Common Name 5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
CAS Number 66635-90-3 Molecular Weight 273.25900
Density N/A Boiling Point N/A
Molecular Formula C15H12FNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid

 Chemical & Physical Properties

Molecular Formula C15H12FNO3
Molecular Weight 273.25900
Exact Mass 273.08000
PSA 59.30000
LogP 2.43010

 Synthetic Route

~77%

5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Structure

5-(4-fluorobenz...

CAS#:66635-90-3

Literature: Syntex (U.S.A.) Inc. Patent: US4347187 A1, 1982 ;

~61%

5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Structure

5-(4-fluorobenz...

CAS#:66635-90-3

Literature: Muchowski; Unger; Ackrell; Cheung; Cooper; Cook; Gallegra; Halpern; Koehler; Kluge Journal of Medicinal Chemistry, 1985 , vol. 28, # 8 p. 1037 - 1049

~%

5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Structure

5-(4-fluorobenz...

CAS#:66635-90-3

Literature: Muchowski; Unger; Ackrell; Cheung; Cooper; Cook; Gallegra; Halpern; Koehler; Kluge Journal of Medicinal Chemistry, 1985 , vol. 28, # 8 p. 1037 - 1049

~%

5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Structure

5-(4-fluorobenz...

CAS#:66635-90-3

Literature: Muchowski; Unger; Ackrell; Cheung; Cooper; Cook; Gallegra; Halpern; Koehler; Kluge Journal of Medicinal Chemistry, 1985 , vol. 28, # 8 p. 1037 - 1049

~%

5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Structure

5-(4-fluorobenz...

CAS#:66635-90-3

Literature: Franco, Fidencio; Greenhouse, Robert; Muchowski, Joseph M. Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1682 - 1688

~%

5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Structure

5-(4-fluorobenz...

CAS#:66635-90-3

Literature: Franco, Fidencio; Greenhouse, Robert; Muchowski, Joseph M. Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1682 - 1688

~%

5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Structure

5-(4-fluorobenz...

CAS#:66635-90-3

Literature: Franco, Fidencio; Greenhouse, Robert; Muchowski, Joseph M. Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1682 - 1688

~%

5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Structure

5-(4-fluorobenz...

CAS#:66635-90-3

Literature: Franco, Fidencio; Greenhouse, Robert; Muchowski, Joseph M. Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1682 - 1688

~%

5-(4-fluorobenzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Structure

5-(4-fluorobenz...

CAS#:66635-90-3

Literature: Franco, Fidencio; Greenhouse, Robert; Muchowski, Joseph M. Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1682 - 1688