Indirubin deriv. 12a

Modify Date: 2025-09-08 16:38:42

Indirubin deriv. 12a Structure
Indirubin deriv. 12a structure
Common Name Indirubin deriv. 12a
CAS Number 667463-65-2 Molecular Weight 341.16
Density N/A Boiling Point N/A
Molecular Formula C16H9BrN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name Indirubin deriv. 12a

 Chemical & Physical Properties

Molecular Formula C16H9BrN2O2
Molecular Weight 341.16
InChIKey RISJOEPLMQEJDE-UHFFFAOYSA-N
SMILES O=C1C(c2c(O)[nH]c3ccccc23)=Nc2cc(Br)ccc21

 Indirubin deriv. 12aBioassay

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Name: Inhibitory activity against Cyclin-dependent kinase 5-p35nck5a
Source: ChEMBL
Target: Cyclin-dependent kinase 5
External Id: CHEMBL663602
Name: Inhibitory activity against GSK-3-alpha/beta from porcine brain
Source: ChEMBL
Target: Glycogen synthase kinase-3 beta
External Id: CHEMBL683003
Name: Cytotoxicity against human KCL22 cells assessed as reduction in cell viability at 1 u...
Source: ChEMBL
Target: KCL-22
External Id: CHEMBL4042004
Name: Cytotoxicity against human KCL22 cells harboring ABL1 T315I mutant assessed as reduct...
Source: ChEMBL
Target: KCL-22
External Id: CHEMBL4042005
Name: Cytotoxicity against human HepG2 cells assessed as cell growth inhibition after 24 hr...
Source: ChEMBL
Target: HepG2
External Id: CHEMBL4044680
Name: Kinase Inhibition Assay from Article 10.1021/jm031016d: "Structural basis for the syn...
Source: BindingDB
Target: N/A
External Id: BindingDB_941_1
Name: Cytoprotective activity against tunicamycin-induced cell death in mouse HT22 cells af...
Source: ChEMBL
Target: HT-22
External Id: CHEMBL4181864
Name: Inhibitory activity against cyclin dependent kinase 1-cyclinB from starfish (Marthast...
Source: ChEMBL
Target: Cyclin-dependent kinase 1
External Id: CHEMBL666598
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