(Lys3)-Bombesin

Modify Date: 2024-01-10 06:44:58

(Lys3)-Bombesin structure	Common Name	(Lys3)-Bombesin
	CAS Number	66839-66-5	Molecular Weight	1591.83
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇₁H₁₁₀N₂₂O₁₈S	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of (Lys3)-Bombesin

[Lys3]-Bombesin is a biological active peptide. (PET (Positron Emission Tomography) imaging of [Lys3]-bombesin is able to detect gastrin-releasing peptide receptor (GRPR) positive prostate cancer. An immunoconjugate of [Lys3]-bombesin and corresponding monoclonal antibody can specifically induce (CD64)-dependent monocyte and neutrophil-mediated lysis of small cell carcinoma.)

Name	[Lys3]-Bombesin,Pyr-QKLGNQWAVGHLM-NH2
Synonym	More Synonyms

Description	[Lys3]-Bombesin is a biological active peptide. (PET (Positron Emission Tomography) imaging of [Lys3]-bombesin is able to detect gastrin-releasing peptide receptor (GRPR) positive prostate cancer. An immunoconjugate of [Lys3]-bombesin and corresponding monoclonal antibody can specifically induce (CD64)-dependent monocyte and neutrophil-mediated lysis of small cell carcinoma.)
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others

Molecular Formula	C₇₁H₁₁₀N₂₂O₁₈S
Molecular Weight	1591.83
Exact Mass	1590.81000
PSA	675.55000
LogP	2.97390

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

Bombesin receptors in distinct tissue compartments of human pancreatic diseases.

Lab. Invest. 80 , 1807-1817, (2000)

Overexpression of receptors for regulatory peptides in various human diseases is reportedly of clinical interest. Among these peptides, bombesin and gastrin-releasing peptide (GRP) have been shown to ...

Modulation of bombesin-induced phosphatidylinositol hydrolysis in a small-cell lung-cancer cell line.

Biochem. J. 255 , 403-410, (1988)

Bombesin is an amphibian tetradecapeptide whose mammalian homologue, gastrin-releasing peptide (GRP), is produced by many small-cell lung-cancer (SCLC) cells, and which can function in an autocrine gr...

Investigation of molecular structure of bombesin and its modified analogues nonadsorbed and adsorbed on electrochemically roughened silver surface.

Biopolymers 89 , 506-521, (2008)

This work describes the molecular structure of bombesin (BN) and its analogs on the basis of the absorption infrared and Raman results described below. In these analogues is replaced one ([D-Phe12]BN,...

bombesin-3-L-lysine

PYROGLU-GLN-LYS-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET NH2

PGLU-GLN-LYS-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2

GLP-GLN-LYS-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2

[LYS3]-BOMBESIN

PYR-QKLGNQWAVGHLM-NH2

PYR-GLN-LYS-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2