(Lys3)-Bombesin

Modify Date: 2024-01-10 06:44:58

(Lys3)-Bombesin Structure
(Lys3)-Bombesin structure
Common Name (Lys3)-Bombesin
CAS Number 66839-66-5 Molecular Weight 1591.83
Density N/A Boiling Point N/A
Molecular Formula C71H110N22O18S Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of (Lys3)-Bombesin


[Lys3]-Bombesin is a biological active peptide. (PET (Positron Emission Tomography) imaging of [Lys3]-bombesin is able to detect gastrin-releasing peptide receptor (GRPR) positive prostate cancer. An immunoconjugate of [Lys3]-bombesin and corresponding monoclonal antibody can specifically induce (CD64)-dependent monocyte and neutrophil-mediated lysis of small cell carcinoma.)

 Names

Name [Lys3]-Bombesin,Pyr-QKLGNQWAVGHLM-NH2
Synonym More Synonyms

 (Lys3)-Bombesin Biological Activity

Description [Lys3]-Bombesin is a biological active peptide. (PET (Positron Emission Tomography) imaging of [Lys3]-bombesin is able to detect gastrin-releasing peptide receptor (GRPR) positive prostate cancer. An immunoconjugate of [Lys3]-bombesin and corresponding monoclonal antibody can specifically induce (CD64)-dependent monocyte and neutrophil-mediated lysis of small cell carcinoma.)
Related Catalog

 Chemical & Physical Properties

Molecular Formula C71H110N22O18S
Molecular Weight 1591.83
Exact Mass 1590.81000
PSA 675.55000
LogP 2.97390

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles3

More Articles
Bombesin receptors in distinct tissue compartments of human pancreatic diseases.

Lab. Invest. 80 , 1807-1817, (2000)

Overexpression of receptors for regulatory peptides in various human diseases is reportedly of clinical interest. Among these peptides, bombesin and gastrin-releasing peptide (GRP) have been shown to ...

Modulation of bombesin-induced phosphatidylinositol hydrolysis in a small-cell lung-cancer cell line.

Biochem. J. 255 , 403-410, (1988)

Bombesin is an amphibian tetradecapeptide whose mammalian homologue, gastrin-releasing peptide (GRP), is produced by many small-cell lung-cancer (SCLC) cells, and which can function in an autocrine gr...

Investigation of molecular structure of bombesin and its modified analogues nonadsorbed and adsorbed on electrochemically roughened silver surface.

Biopolymers 89 , 506-521, (2008)

This work describes the molecular structure of bombesin (BN) and its analogs on the basis of the absorption infrared and Raman results described below. In these analogues is replaced one ([D-Phe12]BN,...

 Synonyms

bombesin-3-L-lysine
PYROGLU-GLN-LYS-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET NH2
PGLU-GLN-LYS-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2
GLP-GLN-LYS-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2
[LYS3]-BOMBESIN
PYR-QKLGNQWAVGHLM-NH2
PYR-GLN-LYS-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2