Methotrexate gamma-Methyl Ester

Modify Date: 2024-01-06 15:47:32

Methotrexate gamma-Methyl Ester Structure
Methotrexate gamma-Methyl Ester structure
Common Name Methotrexate gamma-Methyl Ester
CAS Number 67022-39-3 Molecular Weight 468.47
Density N/A Boiling Point N/A
Molecular Formula C21H24N8O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Methotrexate gamma-Methyl Ester


Methotrexate γ-Methyl Ester (Methotrexate 5-methyl ester) is an impurity of the folate antagonist Methotrexate (HY-14519)[1].

 Names

Name (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
Synonym More Synonyms

 Methotrexate gamma-Methyl Ester Biological Activity

Description Methotrexate γ-Methyl Ester (Methotrexate 5-methyl ester) is an impurity of the folate antagonist Methotrexate (HY-14519)[1].
Related Catalog
References

[1]. James J Fort, et al. Transport and degradation characteristics of methotrexate diallsyl ester prodrugs across tape-stripped hairless mouse skin. Int J Pharm. 1993, 100(1-3): 233-239.

 Chemical & Physical Properties

Molecular Formula C21H24N8O5
Molecular Weight 468.47
Exact Mass 468.18700
PSA 200.27000
LogP 1.25900

 Synonyms

(2S)-2-((4-(((2,4-Diaminopteridin-6-yl)methyl)methylamino)benzoyl)amino)-5-methoxy-5-oxopentanoic acid
L-Glutamic acid,N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-,5-methyl ester
Methotrexate related compound H [USP]
Methotrexate related compound H
Methotrexate specified impurity H [EP]
Methotrexate 5-methyl ester
Methotrexate gamma-Methyl Ester
Methotrexate γ-Methyl Ester