BETA-CHLORNALTREXAMINE 2HCL
BETA-CHLORNALTREXAMINE 2HCL structure
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Common Name | BETA-CHLORNALTREXAMINE 2HCL | ||
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| CAS Number | 67025-98-3 | Molecular Weight | 540.35000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H34Cl4N2O3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
| Name | (4R,4aS,7R,7aR,12bS)-7-[bis(2-chloroethyl)amino]-3-(cyclopropylmethyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol,dihydrochloride |
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| Synonym | More Synonyms |
| Molecular Formula | C24H34Cl4N2O3 |
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| Molecular Weight | 540.35000 |
| Exact Mass | 538.13200 |
| PSA | 56.17000 |
| LogP | 4.64640 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
| RTECS | QC7792000 |
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Methocinnamox is a potent, long-lasting, and selective antagonist of morphine-mediated antinociception in the mouse: comparison with clocinnamox, beta-funaltrexamine, and beta-chlornaltrexamine.
J. Pharmacol. Exp. Ther. 294 , 933, (2000) The irreversible mu-opioid antagonists beta-funaltrexamine (beta-FNA) and beta-chlornaltrexamine (beta-CNA) are important pharmacological tools but have a kappa-agonist activity and, in the latter cas... |
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Relationship between kappa 1 opioid receptor binding and inhibition of adenylyl cyclase in guinea pig brain membranes.
Biochem. Pharmacol. 45(1) , 207-16, (1993) Previously, we showed that kappa-selective ligands inhibit adenylyl cyclase in guinea pig cerebellar membranes. The present studies explore the relationship between kappa 1 binding sites (as determine... |
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Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding.
J. Biol. Chem. 276(37) , 34624-30, (2001) The mu opioid receptor (MOR) plays a central role in mediating acute and chronic effects of narcotic drugs. Three rare single nucleotide polymorphisms in the hMOR gene have been identified that cause ... |
| C24H32Cl2N2O3.2HCl |
| |A-Chlornaltrexamine dihydrochloride |
| |A-CNA |
| chlornaltrexamine hydrochloride |
| Chlornaltrexamine dihydrochloride |