7-methyl-2-phenyl-1H-1,8-naphthyridin-4-one

Modify Date: 2025-10-05 12:54:41

7-methyl-2-phenyl-1H-1,8-naphthyridin-4-one Structure
7-methyl-2-phenyl-1H-1,8-naphthyridin-4-one structure
Common Name 7-methyl-2-phenyl-1H-1,8-naphthyridin-4-one
CAS Number 67159-08-4 Molecular Weight 236.26900
Density N/A Boiling Point N/A
Molecular Formula C15H12N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 7-methyl-2-phenyl-1H-1,8-naphthyridin-4-one
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C15H12N2O
Molecular Weight 236.26900
Exact Mass 236.09500
PSA 46.01000
LogP 3.31080
InChIKey USYVLFNTOOQIMZ-UHFFFAOYSA-N
SMILES Cc1ccc2c(=O)cc(-c3ccccc3)[nH]c2n1

 Synthetic Route

~90%

7-methyl-2-phenyl-1H-1,8-naphthyridin-4-one Structure

7-methyl-2-phen...

CAS#:67159-08-4

Literature: Bristol-Myers Squibb Company Patent: US2008/107624 A1, 2008 ; Location in patent: Page/Page column 48 ;

~54%

7-methyl-2-phenyl-1H-1,8-naphthyridin-4-one Structure

7-methyl-2-phen...

CAS#:67159-08-4

Literature: Katagiri, Nobuya; Kato, Tetsuzo; Niwa, Ryuji Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 407 - 412

~%

7-methyl-2-phenyl-1H-1,8-naphthyridin-4-one Structure

7-methyl-2-phen...

CAS#:67159-08-4

Literature: Katagiri, Nobuya; Kato, Tetsuzo; Niwa, Ryuji Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 407 - 412

 Bioassay

View more

Name: Selectivity, ratio of affinity towards adenosine A3 to A2A
Source: ChEMBL
Target: N/A
External Id: CHEMBL838353
Name: Selectivity, ratio of affinity towards adenosine A3 to A1
Source: ChEMBL
Target: N/A
External Id: CHEMBL838352
Name: Selectivity, ratio of affinity towards adenosine A2A to A1
Source: ChEMBL
Target: N/A
External Id: CHEMBL838351
Name: Ability to displace the specific binding of [3H](R)-PIA to adenosine A3 receptor from...
Source: ChEMBL
Target: Adenosine receptor A3
External Id: CHEMBL642211
Name: Ability to displace the specific binding of [3H]CHA to adenosine A1 receptor from bov...
Source: ChEMBL
Target: Adenosine receptor A1
External Id: CHEMBL638717
Name: Ratio of binding affinity against bovine adenosine A1 to that of A2 receptor
Source: ChEMBL
Target: N/A
External Id: CHEMBL849972
Name: Binding affinity against adenosine A1 receptor in human cortical membranes using [3H]...
Source: ChEMBL
Target: Adenosine receptor A1
External Id: CHEMBL643493
Name: Binding affinity against adenosine A2 receptor in human striatal membranes using [3H]...
Source: ChEMBL
Target: Adenosine receptor A2a
External Id: CHEMBL642332
Name: Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells
Source: ChEMBL
Target: Adenosine receptor A1
External Id: CHEMBL920042
Name: Ratio of binding affinity against human adenosine A1 to that of A2 receptor
Source: ChEMBL
Target: Adenosine receptors; A1 & A2
External Id: CHEMBL849976
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 Synonyms

2-Phenyl-7-methyl-1,8-naphtyridin-4-on
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