1,2,2,3-tetrachloro-1,1,3,3-tetrafluoro-propane

DATA ITEMS CITED :

5

MOLECULAR FORMULA :

C3-Cl4-F4

MOLECULAR WEIGHT :

253.83

WISWESSER LINE NOTATION :

GXFFXGGXGFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

310 mg/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea

REFERENCE :

WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-251,24,1955

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

3640 mg/m3/7H

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - tetany

REFERENCE :

WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-251,26,1955

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

93 mg/kg

TOXIC EFFECTS :

Gastrointestinal - ulceration or bleeding from stomach Gastrointestinal - ulceration or bleeding from small intestine

REFERENCE :

WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-251,24,1955

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

1620 mg/m3/7H

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - tetany

REFERENCE :

WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-251,26,1955

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

3640 mg/m3/7H

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - tetany

REFERENCE :

WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-251,26,1955