GPRP
GPRP structure
|
Common Name | GPRP | ||
|---|---|---|---|---|
| CAS Number | 67869-62-9 | Molecular Weight | 425.48300 | |
| Density | 1.55 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C18H31N7O5 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of GPRPGPRP (Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa)[1][2]. |
| Name | gly-pro-arg-pro |
|---|---|
| Synonym | More Synonyms |
| Description | GPRP (Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa)[1][2]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.55 g/cm3 |
|---|---|
| Molecular Formula | C18H31N7O5 |
| Molecular Weight | 425.48300 |
| Exact Mass | 425.23900 |
| PSA | 194.94000 |
| Index of Refraction | 1.691 |
| Storage condition | −20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| Precursor 9 | |
|---|---|
| DownStream 0 | |
CAS#:41324-66-7
CAS#:134303-72-3
CAS#:85918-68-9
CAS#:23234-71-1![L-Proline,N-[(phenylmethoxy)carbonyl]glycyl-, phenylmethyl ester (9CI) Structure](https://image.chemsrc.com/caspic/230/57294-41-4.png)
CAS#:57294-41-4
CAS#:23828-53-7
CAS#:2188-18-3
CAS#:16652-71-4
CAS#:54046-53-6|
Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi.
J. Thromb. Haemost. 12(8) , 1342-52, (2014) Integrin-linked kinase (ILK) and its associated complex of proteins are involved in many cellular activation processes, including cell adhesion and integrin signaling. We have previously demonstrated ... |
|
|
Platelet function tests, independent of platelet count, are associated with bleeding severity in ITP.
Blood 126 , 873-9, (2015) Immune thrombocytopenia (ITP) patients with similarly low platelet counts differ in their tendency to bleed. To determine if differences in platelet function in ITP patients account for this variation... |
|
|
Procoagulant platelets form an α-granule protein-covered "cap" on their surface that promotes their attachment to aggregates.
J. Biol. Chem. 288(41) , 29621-32, (2013) Strongly activated "coated" platelets are characterized by increased phosphatidylserine (PS) surface expression, α-granule protein retention, and lack of active integrin αIIbβ3. To study how they are ... |
| glycine-proline-arginine-proline |
| FIBRINOLYSIS INHIBITNG FACTOR |
| LAUDANO-DOOLITTLE PEPTIDE |
| GPRP FIBRIN ANTIPOLYMERANT |
| GPRP |
| glycyl-L-prolyl-L-arginyl-L-prolin |
| MFCD00133378 |
| glycyl-prolyl-arginyl-proline |
| FIBRINOLYSIS INHIBITING FACTOR |
| M.W. 425.49 C18H31N7O5 |