Carprazidil

Modify Date: 2024-01-03 16:33:45

Carprazidil Structure
Carprazidil structure
Common Name Carprazidil
CAS Number 68020-77-9 Molecular Weight 291.26300
Density 1.59g/cm3 Boiling Point N/A
Molecular Formula C12H13N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Carprazidil


Carprazidil is a potent vasodilator used to treat severe hypertension and mild heart failure.

 Names

Name methyl N-[5-(3,6-dihydro-2H-pyridin-1-yl)-2-oxo-[1,2,4]oxadiazolo[2,3-a]pyrimidin-7-yl]carbamate
Synonym More Synonyms

 Carprazidil Biological Activity

Description Carprazidil is a potent vasodilator used to treat severe hypertension and mild heart failure.
References 1. Bianchetti MG, et al. Comparative evaluation of the new vasodilator carprazidil and minoxidil in the treatment of moderate to severe hypertension. Eur J Clin Pharmacol. 1982;23(6):483-9.

 Chemical & Physical Properties

Density 1.59g/cm3
Molecular Formula C12H13N5O4
Molecular Weight 291.26300
Exact Mass 291.09700
PSA 101.97000
LogP 0.76510
Index of Refraction 1.712

 Synthetic Route

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Carprazidil Structure

Carprazidil

CAS#:68020-77-9

Literature: Hoffmann-La Roche Inc. Patent: US4549019 A1, 1985 ;

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Carprazidil Structure

Carprazidil

CAS#:68020-77-9

Literature: Hoffmann-La Roche Inc. Patent: US4549019 A1, 1985 ;

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Carprazidil Structure

Carprazidil

CAS#:68020-77-9

Literature: Muller; Ramuz Helvetica Chimica Acta, 1982 , vol. 65, # 5 p. 1445 - 1453

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Carprazidil Structure

Carprazidil

CAS#:68020-77-9

Literature: Muller; Ramuz Helvetica Chimica Acta, 1982 , vol. 65, # 5 p. 1445 - 1453

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Carprazidil Structure

Carprazidil

CAS#:68020-77-9

Literature: Muller; Ramuz Helvetica Chimica Acta, 1982 , vol. 65, # 5 p. 1445 - 1453

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Carprazidil Structure

Carprazidil

CAS#:68020-77-9

Literature: Muller; Ramuz Helvetica Chimica Acta, 1982 , vol. 65, # 5 p. 1445 - 1453

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Carprazidil Structure

Carprazidil

CAS#:68020-77-9

Literature: Hengartner, Urs; Muller, Jean-Claude; Ramuz, Henri Helvetica Chimica Acta, 1983 , vol. 66, # 2 p. 669 - 672

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Carprazidil Structure

Carprazidil

CAS#:68020-77-9

Literature: Muller; Ramuz Helvetica Chimica Acta, 1982 , vol. 65, # 5 p. 1445 - 1453

~%

Carprazidil Structure

Carprazidil

CAS#:68020-77-9

Literature: Hengartner, Urs; Muller, Jean-Claude; Ramuz, Henri Helvetica Chimica Acta, 1983 , vol. 66, # 2 p. 669 - 672

 Synonyms

Carprazidil
Carprazidilum
Carprazidilum [INN-Latin]
methyl 2-oxo-5-(1,2,3,6-tetrahydro-1-pyridyl)-2,8-dihydro<1,2,4>oxadiazolo<2,3-a>pyrimidine-7-carbamate
Carprazadil
Carprazidilo
Methyl 5-(3,6-dihydro-1(2H)-pyridyl)-2-oxo-2H-(1,2,4)oxadiazolo(2,3-a)pyrimidine-7-carbamate