7-O-DeMethyl α-Narcotine

Modify Date: 2025-08-27 13:32:33

7-O-DeMethyl α-Narcotine Structure
7-O-DeMethyl α-Narcotine structure
Common Name 7-O-DeMethyl α-Narcotine
CAS Number 68353-55-9 Molecular Weight 399.39400
Density N/A Boiling Point N/A
Molecular Formula C21H21NO7 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name (S)-7-hydroxy-6-methoxy-3-((R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo-[4,5-g]isoquinolin-5-yl)isobenzofuran-1(3H)-one
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C21H21NO7
Molecular Weight 399.39400
Exact Mass 399.13200
PSA 86.69000
LogP 2.51670
InChIKey ICGJAAVPMLXDHF-AEFFLSMTSA-N
SMILES COc1ccc2c(c1O)C(=O)OC2C1c2c(cc3c(c2OC)OCO3)CCN1C

 Precursor & DownStream

Precursor  0

DownStream  1

 7-O-DeMethyl α-NarcotineBioassay

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Name: Antiproliferative activity against human PLC/PRF/5 cells
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL2032751
Name: Antiproliferative activity against human SNU398 cells
Source: ChEMBL
Target: SNU-398
External Id: CHEMBL2032750
Name: Cell cycle arrest in HEK293EBNA cells by accumulation at S phase cell at 1 uM relativ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL920531
Name: Cell cycle arrest in human PLC/PRF/5 cells assessed as accumulation at G2 phase at 2 ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2032775
Name: Cell cycle arrest in HEK293EBNA cells by accumulation at G2/M phase cell at 1 uM rela...
Source: ChEMBL
Target: N/A
External Id: CHEMBL920532
Name: Cell cycle arrest in human PLC/PRF/5 cells assessed as accumulation at sub-G1 phase a...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2032776
Name: Cell cycle arrest in human PLC/PRF/5 cells assessed as accumulation at G1 phase at 2 ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2032774
Name: Cell cycle arrest in HEK293EBNA cells by accumulation at G1 phase cell at 1 uM relati...
Source: ChEMBL
Target: N/A
External Id: CHEMBL920530
Name: Effect on cell growth in nondividing Swiss 3T3 cells at 50 uM by MTS assay
Source: ChEMBL
Target: NIH3T3
External Id: CHEMBL920540
Name: Cell cycle arrest in human SNU398 cells assessed as accumulation at G1 phase at 2 uM ...
Source: ChEMBL
Target: SNU-398
External Id: CHEMBL2032768
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 Synonyms

7-O-DESMETHYLNOSCAPINE
7-O-Demethyl Alpha-Narcotine
7-O-DeMethyl α-Narcotine
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