2-Toluidine-d7

Modify Date: 2024-04-03 12:48:31

2-Toluidine-d7 Structure
2-Toluidine-d7 structure
Common Name 2-Toluidine-d7
CAS Number 68408-22-0 Molecular Weight 114.19600
Density N/A Boiling Point N/A
Molecular Formula C7H2D7N Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-Toluidine-d7


o-Toluidine-d7 is a deuterated labeled o-Toluidine (HY-41497). o-Toluidine is widely used to measure glucose levels in blood and body fluids. Glucose and primary aromatic amines can condense in glacial acetic acid to form an equilibrium mixture of sugar amines and corresponding Schiff bases. For example, use glacial acetic acid to prepare 6% o-Toluidine, add it to the solution containing the test, and add trichloroacetic acid to remove protein. After heating at 100°C for 10 minutes and rapidly cooling to room temperature, the absorbance at 630 nm can be measured to calculate the glucose level.

 Names

Name 2,3,4,5-tetradeuterio-6-trideuteriomethyl-aniline
Synonym More Synonyms

 2-Toluidine-d7 Biological Activity

Description o-Toluidine-d7 is a deuterated labeled o-Toluidine (HY-41497). o-Toluidine is widely used to measure glucose levels in blood and body fluids. Glucose and primary aromatic amines can condense in glacial acetic acid to form an equilibrium mixture of sugar amines and corresponding Schiff bases. For example, use glacial acetic acid to prepare 6% o-Toluidine, add it to the solution containing the test, and add trichloroacetic acid to remove protein. After heating at 100°C for 10 minutes and rapidly cooling to room temperature, the absorbance at 630 nm can be measured to calculate the glucose level.
Related Catalog
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Molecular Formula C7H2D7N
Molecular Weight 114.19600
Exact Mass 114.11700
PSA 26.02000
LogP 2.15840

 Synonyms

2-Toluidine-d7