2-methyl-6-nitro-2H-indazole

Modify Date: 2025-09-18 11:38:06

2-methyl-6-nitro-2H-indazole Structure
2-methyl-6-nitro-2H-indazole structure
Common Name 2-methyl-6-nitro-2H-indazole
CAS Number 6850-22-2 Molecular Weight 177.16000
Density 1.42g/cm3 Boiling Point 364.5ºC at 760mmHg
Molecular Formula C8H7N3O2 Melting Point N/A
MSDS N/A Flash Point 174.2ºC

 Names

Name 2-methyl-6-nitroindazole
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.42g/cm3
Boiling Point 364.5ºC at 760mmHg
Molecular Formula C8H7N3O2
Molecular Weight 177.16000
Flash Point 174.2ºC
Exact Mass 177.05400
PSA 63.64000
LogP 2.00470
Index of Refraction 1.676
InChIKey RJFYXEGJMSZKIR-UHFFFAOYSA-N
SMILES Cn1cc2ccc([N+](=O)[O-])cc2n1

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NK7951000
CHEMICAL NAME :
2H-Indazole, 2-methyl-6-nitro-
CAS REGISTRY NUMBER :
6850-22-2
BEILSTEIN REFERENCE NO. :
0167038
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H7-N3-O2
MOLECULAR WEIGHT :
177.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
200 nmol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 173,169,1986

 Safety Information

HS Code 2933990090

 Synthetic Route

~77%

2-methyl-6-nitro-2H-indazole Structure

2-methyl-6-nitr...

CAS#:6850-22-2

Literature: Qi, Haofei; Chen, Ligong; Liu, Bingni; Wang, Xinran; Long, Li; Liu, Dengke Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 4 p. 1108 - 1110

~%

2-methyl-6-nitro-2H-indazole Structure

2-methyl-6-nitr...

CAS#:6850-22-2

Literature: Baddam, Sudhakar Reddy; Uday Kumar; Panasa Reddy; Bandichhor, Rakeshwar Tetrahedron Letters, 2013 , vol. 54, # 13 p. 1661 - 1663

~44%

2-methyl-6-nitro-2H-indazole Structure

2-methyl-6-nitr...

CAS#:6850-22-2

Literature: Journal of Chemical Research, Miniprint, , # 11 p. 2601 - 2615

~89%

2-methyl-6-nitro-2H-indazole Structure

2-methyl-6-nitr...

CAS#:6850-22-2

Literature: Baddam, Sudhakar Reddy; Uday Kumar; Panasa Reddy; Bandichhor, Rakeshwar Tetrahedron Letters, 2013 , vol. 54, # 13 p. 1661 - 1663

~89%

2-methyl-6-nitro-2H-indazole Structure

2-methyl-6-nitr...

CAS#:6850-22-2

Literature: Cheung, Mui; Boloor, Amogh; Stafford, Jeffrey A. Journal of Organic Chemistry, 2003 , vol. 68, # 10 p. 4093 - 4095

~51%

2-methyl-6-nitro-2H-indazole Structure

2-methyl-6-nitr...

CAS#:6850-22-2

Detail
Literature: Tetrahedron Letters, , vol. 54, # 13 p. 1661 - 1663

~%

2-methyl-6-nitro-2H-indazole Structure

2-methyl-6-nitr...

CAS#:6850-22-2

Literature: Chemische Berichte, , vol. 37, p. 2583

~%

2-methyl-6-nitro-2H-indazole Structure

2-methyl-6-nitr...

CAS#:6850-22-2

Literature: Chemische Berichte, , vol. 23, p. 3642 Chemische Berichte, , vol. 25, p. 3152

~%

2-methyl-6-nitro-2H-indazole Structure

2-methyl-6-nitr...

CAS#:6850-22-2

Literature: Chemische Berichte, , vol. 37, p. 2583

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 2-methyl-6-nitro-2H-indazoleBioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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 Synonyms

6-NITRO-2-METHYL-2H-INDAZOLE
2H-Indazole,2-methyl-6-nitro
2-Methyl-6-nitro-2H-indazol
2-N-Methyl-6-nitroindazole
2-methyl-6-nitro-indazole
2-Methyl-6-nitro-2H-indazole
2-Methyl-6-nitro-indazol
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