Tuberstemonine

Modify Date: 2024-01-04 07:21:06

Tuberstemonine Structure
Tuberstemonine structure
Common Name Tuberstemonine
CAS Number 6879-01-2 Molecular Weight 375.502
Density 1.2±0.1 g/cm3 Boiling Point 554.2±50.0 °C at 760 mmHg
Molecular Formula C22H33NO4 Melting Point N/A
MSDS N/A Flash Point 289.0±30.1 °C

 Use of Tuberstemonine


Tuberstemonine, an alkaloid, is an antimalarial agent that targets Plasmodium falciparum ferredoxin-NADP+ reductases (pfFNR)[1].

 Names

Name tuberostemonine
Synonym More Synonyms

 Tuberstemonine Biological Activity

Description Tuberstemonine, an alkaloid, is an antimalarial agent that targets Plasmodium falciparum ferredoxin-NADP+ reductases (pfFNR)[1].
Related Catalog
References

[1]. Pudjiastuti P, et al. Inhibitory Activity and Docking Analysis of Antimalarial Agents from Stemona sp. toward Ferredoxin-NADP+ Reductase from Malaria Parasites. J Parasitol Res. 2018 Aug 26;2018:3469132.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 554.2±50.0 °C at 760 mmHg
Molecular Formula C22H33NO4
Molecular Weight 375.502
Flash Point 289.0±30.1 °C
Exact Mass 375.240967
PSA 55.84000
LogP 2.28
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.556
Storage condition 2-8C

 Synthetic Route

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

(2S,7aR,8R,8aS,11S,11aS,11bR,11cR)-8-Ethyl-11-methyl-2-[(2S,4S)-4-methyl-5-oxotetrahydrofuran-2-yl]dodecahydroazepino[3,2,1-hi]furo[3,2-e]indol-10(2H)-one
TuberosteMonin
Tuberstemonine
Azepino[3,2,1-hi]furo[3,2-e]indol-10(2H)-one, 8-ethyldodecahydro-11-methyl-2-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-, (2S,7aR,8R,8aS,11S,11aS,11bR,11cR)-
(2S,7aR,8R,8aS,11S,11aS,11bR,11cR)-8-Ethyl-11-methyl-2-[(2S,4S)-4-methyl-5-oxotetrahydro-2-furanyl]dodecahydroazepino[3,2,1-hi]furo[3,2-e]indol-10(2H)-one