2,4(1H,3H)-Pyrimidinedione, 5-bromo-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-

Modify Date: 2024-01-31 18:14:06

2,4(1H,3H)-Pyrimidinedione, 5-bromo-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)- Structure
2,4(1H,3H)-Pyrimidinedione, 5-bromo-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)- structure
Common Name 2,4(1H,3H)-Pyrimidinedione, 5-bromo-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
CAS Number 69123-97-3 Molecular Weight 325.09
Density N/A Boiling Point N/A
Molecular Formula C9H10BrFN2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2,4(1H,3H)-Pyrimidinedione, 5-bromo-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-


5-Bromo-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-bromouracil
Synonym More Synonyms

  Biological Activity

Description 5-Bromo-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C9H10BrFN2O5
Molecular Weight 325.09
Exact Mass 323.97600
PSA 104.55000

 Synonyms

5-bromo-1-(2-fluoro-β-D-2-deoxy-arabinofuranosyl)-1H-pyrimidine-2,4-dione
1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-bromouracil
2,4(1H,3H)-PYRIMIDINEDIONE,5-BROMO-1-(2-DEOXY-2-FLUORO-B-D-ARABINOFURANOSYL)-