3-Benzofurancarboxylic acid, 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester

Modify Date: 2024-01-07 10:18:28

3-Benzofurancarboxylic acid, 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester Structure
3-Benzofurancarboxylic acid, 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester structure
Common Name 3-Benzofurancarboxylic acid, 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester
CAS Number 691857-53-1 Molecular Weight 339.36000
Density N/A Boiling Point N/A
Molecular Formula C20H18FNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name Ethyl 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-1-benzofuran-3-car boxylate
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C20H18FNO3
Molecular Weight 339.36000
Exact Mass 339.12700
PSA 65.46000
LogP 5.45640

 Synthetic Route

~89%

3-Benzofurancarboxylic acid, 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester Structure

3-Benzofurancar...

CAS#:691857-53-1

Literature: VIROPHARMA INCORPORATED; WYETH Patent: WO2008/24843 A2, 2008 ; Location in patent: Page/Page column 17 ;

~%

3-Benzofurancarboxylic acid, 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester Structure

3-Benzofurancar...

CAS#:691857-53-1

Literature: ABBOTT LABORATORIES; ABBOTT GMBH and CO.KG; MARING, Clarence J.; PRATT, John K.; CARROLL, William A.; LIU, Dachun; BETEBENNER, David A.; HUTCHINSON, Douglas K.; TUFANO, Michael D.; ROCKWAY, Todd W.; SCHOEN, Uwe; PAHL, Axel; WITTE, Adreas Patent: WO2012/87833 A1, 2012 ; WO 2012/087833 A1

~%

3-Benzofurancarboxylic acid, 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester Structure

3-Benzofurancar...

CAS#:691857-53-1

Literature: ABBOTT LABORATORIES; ABBOTT GMBH and CO.KG; MARING, Clarence J.; PRATT, John K.; CARROLL, William A.; LIU, Dachun; BETEBENNER, David A.; HUTCHINSON, Douglas K.; TUFANO, Michael D.; ROCKWAY, Todd W.; SCHOEN, Uwe; PAHL, Axel; WITTE, Adreas Patent: WO2012/87833 A1, 2012 ; WO 2012/087833 A1

~%

3-Benzofurancarboxylic acid, 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester Structure

3-Benzofurancar...

CAS#:691857-53-1

Literature: ABBOTT LABORATORIES; ABBOTT GMBH and CO.KG; MARING, Clarence J.; PRATT, John K.; CARROLL, William A.; LIU, Dachun; BETEBENNER, David A.; HUTCHINSON, Douglas K.; TUFANO, Michael D.; ROCKWAY, Todd W.; SCHOEN, Uwe; PAHL, Axel; WITTE, Adreas Patent: WO2012/87833 A1, 2012 ; WO 2012/087833 A1

~%

3-Benzofurancarboxylic acid, 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester Structure

3-Benzofurancar...

CAS#:691857-53-1

Literature: ABBOTT LABORATORIES; ABBOTT GMBH and CO.KG; MARING, Clarence J.; PRATT, John K.; CARROLL, William A.; LIU, Dachun; BETEBENNER, David A.; HUTCHINSON, Douglas K.; TUFANO, Michael D.; ROCKWAY, Todd W.; SCHOEN, Uwe; PAHL, Axel; WITTE, Adreas Patent: WO2012/87833 A1, 2012 ; WO 2012/087833 A1

~%

3-Benzofurancarboxylic acid, 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester Structure

3-Benzofurancar...

CAS#:691857-53-1

Literature: ABBOTT LABORATORIES; ABBOTT GMBH and CO.KG; MARING, Clarence J.; PRATT, John K.; CARROLL, William A.; LIU, Dachun; BETEBENNER, David A.; HUTCHINSON, Douglas K.; TUFANO, Michael D.; ROCKWAY, Todd W.; SCHOEN, Uwe; PAHL, Axel; WITTE, Adreas Patent: WO2012/87833 A1, 2012 ; WO 2012/087833 A1

~%

3-Benzofurancarboxylic acid, 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester Structure

3-Benzofurancar...

CAS#:691857-53-1

Literature: ABBOTT LABORATORIES; ABBOTT GMBH and CO.KG; MARING, Clarence J.; PRATT, John K.; CARROLL, William A.; LIU, Dachun; BETEBENNER, David A.; HUTCHINSON, Douglas K.; TUFANO, Michael D.; ROCKWAY, Todd W.; SCHOEN, Uwe; PAHL, Axel; WITTE, Adreas Patent: WO2012/87833 A1, 2012 ; WO 2012/087833 A1

~%

3-Benzofurancarboxylic acid, 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester Structure

3-Benzofurancar...

CAS#:691857-53-1

Literature: ABBOTT LABORATORIES; ABBOTT GMBH and CO.KG; MARING, Clarence J.; PRATT, John K.; CARROLL, William A.; LIU, Dachun; BETEBENNER, David A.; HUTCHINSON, Douglas K.; TUFANO, Michael D.; ROCKWAY, Todd W.; SCHOEN, Uwe; PAHL, Axel; WITTE, Adreas Patent: WO2012/87833 A1, 2012 ; WO 2012/087833 A1

 Synonyms

6-amino-5-cyano-2-mercapto-4-phenylpyrimidine
ethyl 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-1-benzofuran-3-carboxylate
ethyl 6-amino-5-cyclopropyl-2-(4-fluorophenyl)benzofuran-3-carboxylate
2-mercapto-4-amino-5-cyano-6-phenylpyrimidine
5-Pyrimidinecarbonitrile,4-amino-1,2-dihydro-6-phenyl-2-thioxo
6-amino-5-cyclopropyl-2-(4-fluoro-phenyl)-benzofuran-3-carboxylic acid ethyl ester