1-Boc-2-(4-tetrahydropyranyl)hydrazine

Modify Date: 2024-01-10 11:43:14

1-Boc-2-(4-tetrahydropyranyl)hydrazine Structure
1-Boc-2-(4-tetrahydropyranyl)hydrazine structure
 Common Name 1-Boc-2-(4-tetrahydropyranyl)hydrazine
CAS Number 693287-79-5 Molecular Weight 216.27700
Density N/A Boiling Point N/A
Molecular Formula C10H20N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name tert-Butyl 2-(tetrahydro-2H-pyran-4-yl)hydrazinecarboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C10H20N2O3
Molecular Weight 216.27700
Exact Mass 216.14700
PSA 59.59000
LogP 1.97650

 Safety Information

HS Code 2934999090

 Synthetic Route

Tetrahydro-2H-pyran-4-one structure

Tetrahydro-2H-p...

CAS#:29943-42-8

tert-Butyl carbazate structure

tert-Butyl carbazate

CAS#:870-46-2

~89%

1-Boc-2-(4-tetrahydropyranyl)hydrazine Structure

1-Boc-2-(4-tetr...

CAS#:693287-79-5

Literature: McDonald, Iain M.; Austin, Carol; Buck, Ildiko M.; Dunstone, David J.; Gaffen, John; Griffin, Eric; Harper, Elaine A.; Hull, Robert A. D.; Kalindjian, S. Barret; Linney, Ian D.; Low, Caroline M. R.; Patel, Dipa; Pether, Michael J.; Raynor, Michelle; Roberts, Sonia P.; Shaxted, Mark E.; Spencer, John; Steel, Katherine I. M.; Sykes, David A.; Wright, Paul T.; Xun, Wei Journal of Medicinal Chemistry, 2007 , vol. 50, # 20 p. 4789 - 4792
Hydrazinecarboxylic acid, (tetrahydro-4H-pyran-4-ylidene)-, 1,1-dimethylethyl structure

Hydrazinecarbox...

CAS#:693287-78-4

~99%

1-Boc-2-(4-tetrahydropyranyl)hydrazine Structure

1-Boc-2-(4-tetr...

CAS#:693287-79-5

Literature: TYROGENEX, INC.; LIANG, Congxin; LI, Zhigang Patent: WO2010/56320 A2, 2010 ; Location in patent: Page/Page column 54 ; WO 2010/056320 A2
Tetrahydro-2H-pyran-4-one structure

Tetrahydro-2H-p...

CAS#:29943-42-8

tert-Butyl carbazate structure

tert-Butyl carbazate

CAS#:870-46-2

acetic acid structure

acetic acid

CAS#:64-19-7

~0%

N/A structure

N/A

CAS#:1082745-70-7

Detail
Literature: Pfizer Inc Patent: US2009/30003 A1, 2009 ; Location in patent: Page/Page column 35-36 ; US 20090030003 A1
acetic acid structure

acetic acid

CAS#:64-19-7

Hydrazinecarboxylic acid, (tetrahydro-4H-pyran-4-ylidene)-, 1,1-dimethylethyl structure

Hydrazinecarbox...

CAS#:693287-78-4

~%

N/A structure

N/A

CAS#:1082745-70-7

1-Boc-2-(4-tetrahydropyranyl)hydrazine Structure

1-Boc-2-(4-tetr...

CAS#:693287-79-5

Literature: PFIZER INC. Patent: WO2008/139293 A1, 2008 ; Location in patent: Page/Page column 90; 46 ;
Tetrahydro-2H-pyran-4-one structure

Tetrahydro-2H-p...

CAS#:29943-42-8

~%

1-Boc-2-(4-tetrahydropyranyl)hydrazine Structure

1-Boc-2-(4-tetr...

CAS#:693287-79-5

Literature: Ranatunge, Ramani R.; Augustyniak, Michael; Bandarage, Upul K.; Earl, Richard A.; Ellis, James L.; Garvey, David S.; Janero, David R.; Letts, L. Gordon; Martino, Allison M.; Murty, Madhavi G.; Richardson, Stewart K.; Schroeder, Joseph D.; Shumway, Matthew J.; Tam, S. William; Trocha, A. Mark; Young, Delano V. Journal of Medicinal Chemistry, 2004 , vol. 47, # 9 p. 2180 - 2193
tert-Butyl carbazate structure

tert-Butyl carbazate

CAS#:870-46-2

~%

1-Boc-2-(4-tetrahydropyranyl)hydrazine Structure

1-Boc-2-(4-tetr...

CAS#:693287-79-5

Literature: Ranatunge, Ramani R.; Augustyniak, Michael; Bandarage, Upul K.; Earl, Richard A.; Ellis, James L.; Garvey, David S.; Janero, David R.; Letts, L. Gordon; Martino, Allison M.; Murty, Madhavi G.; Richardson, Stewart K.; Schroeder, Joseph D.; Shumway, Matthew J.; Tam, S. William; Trocha, A. Mark; Young, Delano V. Journal of Medicinal Chemistry, 2004 , vol. 47, # 9 p. 2180 - 2193
Tetrahydro-2H-pyran-4-one structure

Tetrahydro-2H-p...

CAS#:29943-42-8

tert-Butyl carbazate structure

tert-Butyl carbazate

CAS#:870-46-2

acetic acid structure

acetic acid

CAS#:64-19-7

~%

Hydrazinecarboxylic acid, 2-acetyl-, 1,1-dimethylethyl ester (9CI) structure

Hydrazinecarbox...

CAS#:90271-04-8

Detail
Literature: Verhoest, Patrick R.; Fonseca, Kari R.; Hou, Xinjun; Proulx-Lafrance, Caroline; Corman, Michael; Helal, Christopher J.; Claffey, Michelle M.; Tuttle, Jamison B.; Coffman, Karen J.; Liu, Shenpinq; Nelson, Frederick; Kleiman, Robin J.; Menniti, Frank S.; Schmidt, Christopher J.; Vanase-Frawley, Michelle; Liras, Spiros Journal of Medicinal Chemistry, 2012 , vol. 55, # 21 p. 9045 - 9054

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

tert-butyl N-(oxan-4-ylamino)carbamate
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