2'-O-t-Butyldimethylsilyl adenosine

Modify Date: 2024-01-03 23:45:20

2'-O-t-Butyldimethylsilyl adenosine Structure
2'-O-t-Butyldimethylsilyl adenosine structure
Common Name 2'-O-t-Butyldimethylsilyl adenosine
CAS Number 69504-13-8 Molecular Weight 381.50200
Density N/A Boiling Point N/A
Molecular Formula C16H27N5O4Si Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2'-O-t-Butyldimethylsilyl adenosine


2’-O-t-Butyldimethylsilyladenosine is a adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

 Names

Name (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[tert-butyl(dimethyl)silyl]oxy-2-(hydroxymethyl)oxolan-3-ol
Synonym More Synonyms

 2'-O-t-Butyldimethylsilyl adenosine Biological Activity

Description 2’-O-t-Butyldimethylsilyladenosine is a adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

 Chemical & Physical Properties

Molecular Formula C16H27N5O4Si
Molecular Weight 381.50200
Exact Mass 381.18300
PSA 128.54000
LogP 1.63070

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

Adenosine,2'-O-[(1,1-dimethylethyl)dimethylsilyl]