NF864

Modify Date: 2025-11-14 10:58:21

NF864 Structure
NF864 structure
Common Name NF864
CAS Number 69606-09-3 Molecular Weight 1872.66
Density N/A Boiling Point N/A
Molecular Formula C57H40N6NaO41S12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NF864


NF864, a suramin analog, is a P2X1 receptor inhibitor.

 Names

Name NF864

 NF864 Biological Activity

Description NF864, a suramin analog, is a P2X1 receptor inhibitor.
References 1. Horner S, Menke K, Hildebrandt C, Kassack MU, Nickel P, Ullmann H, Mahaut-Smith MP, Lambrecht G. The novel suramin analogue NF864 selectively blocks P2X1 receptors in human platelets with potency in the low nanomolar range. Naunyn Schmiedebergs Arch Pharmacol. 2005 Jul;372(1):1-13. Epub 2005 Sep 13. PubMed PMID: 16158305.

 Chemical & Physical Properties

Molecular Formula C57H40N6NaO41S12
Molecular Weight 1872.66
InChIKey RJWQTMJSJNVWPW-UHFFFAOYSA-N
SMILES O=C(Nc1cc(C(=O)Nc2ccc(S(=O)(=O)O)c3cc(S(=O)(=O)O)cc(S(=O)(=O)O)c23)cc(C(=O)Nc2ccc(S(=O)(=O)O)c3cc(S(=O)(=O)O)cc(S(=O)(=O)O)c23)c1)Nc1cc(C(=O)Nc2ccc(S(=O)(=O)O)c3cc(S(=O)(=O)O)cc(S(=O)(=O)O)c23)cc(C(=O)Nc2ccc(S(=O)(=O)O)c3cc(S(=O)(=O)O)cc(S(=O)(=O)O)c23)c1.[Na]
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