H-Phe-Leu-Glu-Glu-Leu-OH

Modify Date: 2024-01-14 12:13:14

H-Phe-Leu-Glu-Glu-Leu-OH structure	Common Name	H-Phe-Leu-Glu-Glu-Leu-OH
	CAS Number	69729-06-2	Molecular Weight	649.73
	Density	1.259g/cm3	Boiling Point	1059.8ºC at 760 mmHg
	Molecular Formula	C₃₁H₄₇N₅O₁₀	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	594.8ºC

Use of H-Phe-Leu-Glu-Glu-Leu-OH

H-Phe-Leu-Glu-Glu-Leu-OH is a synthetic pentapeptide, which can be used as the substrate of vitamin K dependent carboxylase, and a glutamyl residue in the generated product is carboxylated[1][2].

Name	H-Phe-Leu-Glu-Glu-Leu-OH
Synonym	More Synonyms

Description	H-Phe-Leu-Glu-Glu-Leu-OH is a synthetic pentapeptide, which can be used as the substrate of vitamin K dependent carboxylase, and a glutamyl residue in the generated product is carboxylated[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Rich DH, et al. Synthesis of peptide analogues of prothrombin precursor sequence 5-9. Substrate specificity of vitamin K dependent carboxylase. J Med Chem. 1981 Jun;24(6):706-11. [2]. Rich DH, et al. Synthesis and biological properties of new hexapeptide substrates for vitamin K dependent carboxylase. Evidence for X-Pro cis/trans amide bond interconversions in prothrombin precursor fragment 18-23. J Med Chem. 1983 Jun;26(6):910-6.

Description

H-Phe-Leu-Glu-Glu-Leu-OH is a synthetic pentapeptide, which can be used as the substrate of vitamin K dependent carboxylase, and a glutamyl residue in the generated product is carboxylated[1][2].

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Rich DH, et al. Synthesis of peptide analogues of prothrombin precursor sequence 5-9. Substrate specificity of vitamin K dependent carboxylase. J Med Chem. 1981 Jun;24(6):706-11.

[2]. Rich DH, et al. Synthesis and biological properties of new hexapeptide substrates for vitamin K dependent carboxylase. Evidence for X-Pro cis/trans amide bond interconversions in prothrombin precursor fragment 18-23. J Med Chem. 1983 Jun;26(6):910-6.

Density	1.259g/cm3
Boiling Point	1059.8ºC at 760 mmHg
Molecular Formula	C₃₁H₄₇N₅O₁₀
Molecular Weight	649.73
Flash Point	594.8ºC
Exact Mass	649.33200
PSA	254.32000
LogP	2.66590
Index of Refraction	1.551

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

Expression and characterization of recombinant vitamin K-dependent gamma-glutamyl carboxylase from an invertebrate, Conus textile.

Eur. J. Biochem. 269 , 6162-6172, (2002)

The marine snail Conus is the sole invertebrate wherein both the vitamin K-dependent carboxylase and its product, gamma-carboxyglutamic acid, have been identified. To examine its biosynthesis of gamma...

Isolation and partial characterization of a vitamin K-dependent carboxylase from bovine aortae.

Biochem. J. 245 , 251-255, (1987)

Vitamin K-dependent carboxylase activity has been demonstrated in the crude microsomal fraction of the intima of bovine aortae. The procedure for the isolation of vessel wall carboxylase is a slight m...

Vitamin K-dependent carboxylase: purification of the rat liver microsomal enzyme.

Arch. Biochem. Biophys. 202 , 515, (1980)

PHE-LEU-GLU-GLU-LEU

FLEEL

phenylalanine-leucine-glutamine-glutamine-leucine

MFCD00076877