Coelenterazine 400 a

Modify Date: 2024-01-03 13:30:30

Coelenterazine 400 a Structure
Coelenterazine 400 a structure
Common Name Coelenterazine 400 a
CAS Number 70217-82-2 Molecular Weight 391.464
Density 1.2±0.1 g/cm3 Boiling Point 551.4±60.0 °C at 760 mmHg
Molecular Formula C26H21N3O Melting Point N/A
MSDS N/A Flash Point 287.3±32.9 °C

 Use of Coelenterazine 400 a


Coelenteramine 400a (Bisdeoxycoelenterazine), a derivative of Coelenterazine, is a Renilla luciferase (RLuc) substrate. In the presence of Coelenteramine 400a, RLuc can emit blue light at 395 nm[1][2].

 Names

Name 2,8-dibenzyl-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one
Synonym More Synonyms

 Coelenterazine 400 a Biological Activity

Description Coelenteramine 400a (Bisdeoxycoelenterazine), a derivative of Coelenterazine, is a Renilla luciferase (RLuc) substrate. In the presence of Coelenteramine 400a, RLuc can emit blue light at 395 nm[1][2].
Related Catalog
References

[1]. Levi J, et, al. Bisdeoxycoelenterazine derivatives for improvement of bioluminescence resonance energy transfer assays. J Am Chem Soc. 2007 Oct 3;129(39):11900-1.

[2]. Bertrand L, et, al. The BRET2/arrestin assay in stable recombinant cells: a platform to screen for compounds that interact with G protein-coupled receptors (GPCRS). J Recept Signal Transduct Res. Feb-Nov 2002;22(1-4):533-41.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 551.4±60.0 °C at 760 mmHg
Molecular Formula C26H21N3O
Molecular Weight 391.464
Flash Point 287.3±32.9 °C
Exact Mass 391.168457
PSA 50.16000
LogP 4.84
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.662

 Synonyms

BlueSyn C
DI-DEHYDRO COELENTERAZINE
Imidazo[1,2-a]pyrazin-3(7H)-one, 6-phenyl-2,8-bis(phenylmethyl)-
2,8-Dibenzyl-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one
Coelenterazine 400 a
BISDEOXYCOELENTERAZINE
C-7010
coelenterazine-hh