10,11-dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine

Modify Date: 2026-08-03 19:51:17

10,11-dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine Structure
10,11-dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine structure
Common Name 10,11-dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine
CAS Number 70449-94-4 Molecular Weight 221.30
Density 1.144g/cm3 Boiling Point 320.3ºC at 760 mmHg
Molecular Formula C16H15N Melting Point N/A
MSDS N/A Flash Point 152.6ºC

 Use of 10,11-dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine


(Rac)-Dizocilpine ((Rac)-MK-801) is the racemate of Dizocilpine (HY-15084B). Dizocilpine (MK-801), a potent anticonvulsant, is a selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist[1].

 Names

Name Neurogard
Synonym More Synonyms

  Biological Activity

Description (Rac)-Dizocilpine ((Rac)-MK-801) is the racemate of Dizocilpine (HY-15084B). Dizocilpine (MK-801), a potent anticonvulsant, is a selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist[1].
Related Catalog
References

[1]. Wong EH, et al. The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc Natl Acad Sci U S A. 1986 Sep;83(18):7104-8.  

 Chemical & Physical Properties

Density 1.144g/cm3
Boiling Point 320.3ºC at 760 mmHg
Molecular Formula C16H15N
Molecular Weight 221.30
Flash Point 152.6ºC
Exact Mass 221.12000
PSA 12.03000
LogP 3.47930
Index of Refraction 1.632
InChIKey LBOJYSIDWZQNJS-UHFFFAOYSA-N
SMILES CC12NC(Cc3ccccc31)c1ccccc12

 Bioassay

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Name: Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-p1-antagonist
Name: qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2
Source: NCGC
Target: eyes absent homolog 2 isoform a [Homo sapiens]
External Id: EYA2477
Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
Name: qHTS Validation Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2...
Source: NCGC
Target: ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens]
External Id: UBCH001
Name: The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre...
Source: 11924
Target: N/A
External Id: CGM data for Cell Systems paper Dec 2015
Name: qHTS screen for enhancers of Arylsulfatase A (ASA1): LOPAC Validation Assay
Source: NCGC
Target: arylsulfatase A [Homo sapiens]
External Id: asa1-v2
Name: Primary qHTS for inhibitors of La Crosse Virus (LACV) - induced cell death in SH-SY5Y...
Source: NCGC
Target: N/A
External Id: TRND-LACV-FDA-LOPAC
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 Synonyms

DIZOCILPINE
10,11-dihydro-5-methyl-5H-dibenzo<a,d>cyclohepten-5,10-imine
Dizocilpinum
Dizocilpina
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