beta-L-D4A

Modify Date: 2024-01-07 16:55:12

beta-L-D4A Structure
beta-L-D4A structure
Common Name beta-L-D4A
CAS Number 7057-48-9 Molecular Weight 233.22700
Density 1.74 g/cm3 Boiling Point 553.9ºC at 760 mmHg
Molecular Formula C10H11N5O2 Melting Point 187-189ºC
MSDS N/A Flash Point 288.8ºC

 Use of beta-L-D4A


NSC 108602 is a nucleoside HIV-1 reverse transcriptase inhibitor.

 Names

Name 2',3'-dideoxy-2',3'-didehydroadenosine
Synonym More Synonyms

 beta-L-D4A Biological Activity

Description NSC 108602 is a nucleoside HIV-1 reverse transcriptase inhibitor.
Related Catalog
Target

HIV-1

In Vitro NSC 108602 (d4A) is a nucleoside HIV-1 reverse transcriptase inhibitor. Results confirm that the biological activity of NSC 108602 is connected with the termination of the DNA chain synthesis in the 5′-3′ direction[1].
References

[1]. Ponomareva AG, et al. Structural and energetic properties of the potential HIV-1 reverse transcriptase inhibitors d4A and d4G: a comprehensive theoretical investigation. J Biomol Struct Dyn. 2014;32(5):730-40.

 Chemical & Physical Properties

Density 1.74 g/cm3
Boiling Point 553.9ºC at 760 mmHg
Melting Point 187-189ºC
Molecular Formula C10H11N5O2
Molecular Weight 233.22700
Flash Point 288.8ºC
Exact Mass 233.09100
PSA 99.08000
LogP 0.43560
Index of Refraction 1.822

 Safety Information

Hazard Codes Xn

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

D4A
2',3'-Dideoxy-2'3'-didehy...
2'3'-didehydro-2'3'-dideoxyadenosine
((2S,5R)-5-(6-Amino-9H-purin-9-yl)-2,5-dihydrofuran-2-yl)methanol
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