2-Phenylimidazo(2,1-a)isoquinoline

Modify Date: 2025-08-26 14:46:20

2-Phenylimidazo(2,1-a)isoquinoline Structure
2-Phenylimidazo(2,1-a)isoquinoline structure
Common Name 2-Phenylimidazo(2,1-a)isoquinoline
CAS Number 70845-68-0 Molecular Weight 244.29100
Density 1.17g/cm3 Boiling Point N/A
Molecular Formula C17H12N2 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 2-phenylimidazo[2,1-a]isoquinoline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.17g/cm3
Molecular Formula C17H12N2
Molecular Weight 244.29100
Exact Mass 244.10000
PSA 17.30000
LogP 4.15450
Index of Refraction 1.671
InChIKey LKENZGMGOAVEHZ-UHFFFAOYSA-N
SMILES c1ccc(-c2cn3ccc4ccccc4c3n2)cc1

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NI3029000
CHEMICAL NAME :
Imidazo(2,1-a)isoquinoline, 2-phenyl-
CAS REGISTRY NUMBER :
70845-68-0
BEILSTEIN REFERENCE NO. :
0015101
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C17-H12-N2
MOLECULAR WEIGHT :
244.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
15 mg/kg
SEX/DURATION :
female 6-10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 33,1222,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
1250 ug/kg
SEX/DURATION :
female 4-8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 33,1222,1983

 Synthetic Route

 2-Phenylimidazo(2,1-a)isoquinolineBioassay

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Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
Name: Inhibitors of CDC25B-CDK2/CyclinA interaction
Source: Center for Chemical Genomics, University of Michigan
External Id: MScreen:TargetID_600
Name: High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS1303
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN
Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
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 Synonyms

Imidazo(2,1-a)isoquinoline,2-phenyl
2-Phenyl-imidazo<2.1-a>isochinolin
2-Phenylimidazo(2,1-a)isoquinoline
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