PYCR1-IN-1
PYCR1-IN-1 structure
|
Common Name | PYCR1-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 709-85-3 | Molecular Weight | 238.12 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H12BrN | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PYCR1-IN-1PYCR1-IN-1 (compound 4) is a pyrroline-5-carboxylate reductase 1 (PYCR1) inhibitor with an IC50 of 8.8 µM. PYCR1-IN-1 has anticancer effects[1]. |
| Name | PYCR1-IN-1 |
|---|
| Description | PYCR1-IN-1 (compound 4) is a pyrroline-5-carboxylate reductase 1 (PYCR1) inhibitor with an IC50 of 8.8 µM. PYCR1-IN-1 has anticancer effects[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 8.8 µM (PYCR1)[1] |
| References |
| Molecular Formula | C11H12BrN |
|---|---|
| Molecular Weight | 238.12 |
|
Name: Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli...
Source: ChEMBL
Target: Pyrroline-5-carboxylate reductase 1, mitochondrial
External Id: CHEMBL4387563
|
|
Name: Potency index, ratio of IC50 of pargyline to IC50 for test compound for inhibition of...
Source: ChEMBL
Target: Pyrroline-5-carboxylate reductase 1, mitochondrial
External Id: CHEMBL4387586
|
|
Name: Effect on valine content in human SUM159PT cells at 1 to 100 uM by LC-MS analysis rel...
Source: ChEMBL
Target: SUM-159-PT
External Id: CHEMBL4387577
|
|
Name: Effect on isoleucine content in human SUM159PT cells at 1 to 100 uM by LC-MS analysis...
Source: ChEMBL
Target: SUM-159-PT
External Id: CHEMBL4387578
|
|
Name: Inhibition of PYCR1 in human SUM159PT cells assessed as reduction proline M+5 content...
Source: ChEMBL
Target: Pyrroline-5-carboxylate reductase 1, mitochondrial
External Id: CHEMBL4387580
|
|
Name: Inhibition of PYCR1 in human MDA-MB-231 cells assessed as reduction in cell number at...
Source: ChEMBL
Target: Pyrroline-5-carboxylate reductase 1, mitochondrial
External Id: CHEMBL4387581
|
|
Name: Inhibition of PYCR1 in human SUM159PT cells assessed as reduction in cell number at 1...
Source: ChEMBL
Target: Pyrroline-5-carboxylate reductase 1, mitochondrial
External Id: CHEMBL4387582
|
|
Name: Inhibition of PYCR1 in human MDA-MB-231 cells assessed as reduction in cell number at...
Source: ChEMBL
Target: Pyrroline-5-carboxylate reductase 1, mitochondrial
External Id: CHEMBL4387583
|
|
Name: Inhibition of PYCR1 in human SUM159PT cells assessed as reduction in cell number at 1...
Source: ChEMBL
Target: Pyrroline-5-carboxylate reductase 1, mitochondrial
External Id: CHEMBL4387584
|
|
Name: Toxicity in human SUM159PT cells assessed as reduction in cell viability at 100 uM
Source: ChEMBL
Target: SUM-159-PT
External Id: CHEMBL4387571
|
Total 15, Current Page 1 of 2
1
2