Kyotorphin acetate salt

Modify Date: 2026-07-11 20:08:37

Kyotorphin acetate salt Structure
Kyotorphin acetate salt structure
Common Name Kyotorphin acetate salt
CAS Number 70904-56-2 Molecular Weight 337.37400
Density 1.43 g/cm3 Boiling Point N/A
Molecular Formula C15H23N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Kyotorphin acetate salt


Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients[1].

 Names

Name L-tyrosyl-L-arginine
Synonym More Synonyms

 Kyotorphin acetate salt Biological Activity

Description Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients[1].
Related Catalog
In Vitro The analgesic effect of kyotorphin is determined by means of the hot-plate test, with an ED50 value of 5.3 μg/animal (15.7 nmole/animal)[1].
References

[1]. Takagi H, et al. Morphine-like analgesia by a new dipeptide, L-tyrosyl-L-arginine (Kyotorphin) and its analogue. Eur J Pharmacol. 1979;55(1):109-111.

 Chemical & Physical Properties

Density 1.43 g/cm3
Molecular Formula C15H23N5O4
Molecular Weight 337.37400
Exact Mass 337.17500
PSA 174.55000
LogP 1.37680
InChIKey JXNRXNCCROJZFB-RYUDHWBXSA-N
SMILES NC(N)=NCCCC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)O

 Kyotorphin acetate saltBioassay

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Name: Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-p1-antagonist
Name: Compound was evaluated for brain targeted delivery system by Tail flick latency as an...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL786292
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
Name: qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar...
Source: NCGC
Target: 67.9K protein [Vaccinia virus]
External Id: Vaccinia-p2mCherry
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
Name: qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary ...
Source: NCGC
Target: 67.9K protein [Vaccinia virus]
External Id: Vaccinia-p2Venus
Name: Analgesic activity in ICR mouse assessed as pain threshold at 1 umol/kg administered ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL3790028
Name: Analgesic activity in ICR mouse assessed as pain threshold at 1 umol/kg administered ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL3790027
Name: Analgesic activity in ICR mouse assessed as pain threshold at 1 umol/kg administered ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL3790026
Name: Analgesic activity in ICR mouse assessed as pain threshold at 1 umol/kg administered ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL3790025
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 Synonyms

D-Kyotorphin
Tyr-arg
L-Arginine,N2-L-tyrosyl
L-Tyr-L-Arg
L-Araginine,L-tyrosyl
kyotorphin
Arginine,N2-tyrosyl
Kiotorphin
L-Tyrosyl-L-arginine
(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
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