2'-C-Methyl isoguanosine

Modify Date: 2024-01-12 08:47:45

2'-C-Methyl isoguanosine Structure
2'-C-Methyl isoguanosine structure
Common Name 2'-C-Methyl isoguanosine
CAS Number 714249-83-9 Molecular Weight 297.27
Density 2.0±0.1 g/cm3 Boiling Point N/A
Molecular Formula C11H15N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2'-C-Methyl isoguanosine


2′-β-C-Methyl isoguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2'-C-Methyl-2-oxo-3-hydroadenosine
Synonym More Synonyms

 2'-C-Methyl isoguanosine Biological Activity

Description 2′-β-C-Methyl isoguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Molecular Formula C11H15N5O5
Molecular Weight 297.27
Exact Mass 297.107330
LogP -1.36
Index of Refraction 1.860

 Synonyms

3-Hydroadenosine, 2'-C-methyl-2-oxo-
2'-C-Methyl-2-oxo-3-hydroadenosine
MFCD25542509