(S)-Amisulpride
Modify Date: 2025-08-27 12:09:14
(S)-Amisulpride structure
|
Common Name | (S)-Amisulpride | ||
|---|---|---|---|---|
| CAS Number | 71675-92-8 | Molecular Weight | 369.48 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 558.9±50.0 °C at 760 mmHg | |
| Molecular Formula | C17H27N3O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 291.8±30.1 °C | |
Use of (S)-Amisulpride(S)-Amisulpride (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a KI of 900 nM. (S)-Amisulpride has antipsychotic and antidepressant effects[1][2]. |
| Name | ES3TWM82E8 |
|---|---|
| Synonym | More Synonyms |
| Description | (S)-Amisulpride (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a KI of 900 nM. (S)-Amisulpride has antipsychotic and antidepressant effects[1][2]. |
|---|---|
| Related Catalog | |
| Target |
D2 Receptor D3 Receptor 5-HT7 Receptor:900 nM (Ki) |
| In Vitro | (S)-Amisulpride (Esamisulpride) displays high affinity binding at both D2 and D3 receptors and is approximately twice as potent as racamisulpride and 20–50 times more potent than (R)-amisulpride at these receptors[2] |
| In Vivo | The (S)-amisulpride (10mg/kg, s.c.) stimulus is rapidly acquired and was shown to be dose-related, time dependent (effective between 30 and 120min) and stereoselective male C57BL/6 mice[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 558.9±50.0 °C at 760 mmHg |
| Molecular Formula | C17H27N3O4S |
| Molecular Weight | 369.48 |
| Flash Point | 291.8±30.1 °C |
| Exact Mass | 369.172241 |
| LogP | 1.60 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.546 |
| 4-Amino-N-{[(2S)-1-ethyl-2-pyrrolidinyl]methyl}-5-(ethylsulfonyl)-2-methoxybenzamide |
| EINECS 275-831-7 |
| (S)-AMISULPRIDE |
| Benzamide, 4-amino-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-5-(ethylsulfonyl)-2-methoxy- |
| ES3TWM82E8 |