[4-(Diethoxy-phosphorylamino)-butyl]-phosphoramidic acid diethyl ester

Modify Date: 2024-01-30 20:30:31

[4-(Diethoxy-phosphorylamino)-butyl]-phosphoramidic acid diethyl ester structure	Common Name	[4-(Diethoxy-phosphorylamino)-butyl]-phosphoramidic acid diethyl ester
	CAS Number	720707-93-7	Molecular Weight	360.32
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₃₀N₂O₆P₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of [4-(Diethoxy-phosphorylamino)-butyl]-phosphoramidic acid diethyl ester

Tetraethyl butane-1,4-diylbis(phosphoramidate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Tetraethyl butane-1,4-diylbis(phosphoramidate)
Synonym	More Synonyms

Description	Tetraethyl butane-1,4-diylbis(phosphoramidate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₂H₃₀N₂O₆P₂
Molecular Weight	360.32

MFCD25424110