1,2'-O-Dimethylguanosine

Modify Date: 2024-04-02 20:31:01

1,2'-O-Dimethylguanosine Structure
1,2'-O-Dimethylguanosine structure
Common Name 1,2'-O-Dimethylguanosine
CAS Number 73667-71-7 Molecular Weight 311.29
Density N/A Boiling Point N/A
Molecular Formula C12H17N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1,2'-O-Dimethylguanosine


1,2'-O-Dimethylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

 Names

Name 1,2'-Dimethylguanosine

 1,2'-O-Dimethylguanosine Biological Activity

Description 1,2'-O-Dimethylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog
References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.  

 Chemical & Physical Properties

Molecular Formula C12H17N5O5
Molecular Weight 311.29
Exact Mass 311.12300
PSA 137.65000