N-benzylpyrazin-2-amine

Modify Date: 2025-08-21 20:14:30

N-benzylpyrazin-2-amine Structure
N-benzylpyrazin-2-amine structure
Common Name N-benzylpyrazin-2-amine
CAS Number 7375-45-3 Molecular Weight 185.22500
Density 1.187g/cm3 Boiling Point 329.6ºC at 760 mmHg
Molecular Formula C11H11N3 Melting Point N/A
MSDS N/A Flash Point 153.1ºC

 Names

Name N-benzylpyrazin-2-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.187g/cm3
Boiling Point 329.6ºC at 760 mmHg
Molecular Formula C11H11N3
Molecular Weight 185.22500
Flash Point 153.1ºC
Exact Mass 185.09500
PSA 37.81000
LogP 2.16170
Index of Refraction 1.644
InChIKey ITELDXFJDCTYAQ-UHFFFAOYSA-N
SMILES c1ccc(CNc2cnccn2)cc1

 Synthetic Route

~88%

N-benzylpyrazin-2-amine Structure

N-benzylpyrazin...

CAS#:7375-45-3

Literature: Tardiff, Bennett J.; Stradiotto, Mark European Journal of Organic Chemistry, 2012 , # 21 p. 3972 - 3977

~91%

N-benzylpyrazin-2-amine Structure

N-benzylpyrazin...

CAS#:7375-45-3

Literature: Donthiri, Ramachandra Reddy; Pappula, Venkatanarayana; Chandra Mohan, Darapaneni; Gaywala, Hiren H.; Adimurthy, Subbarayappa Journal of Organic Chemistry, 2013 , vol. 78, # 13 p. 6775 - 6781

~%

N-benzylpyrazin-2-amine Structure

N-benzylpyrazin...

CAS#:7375-45-3

Literature: O'Connor, Stephen J.; Barr, Kenneth J.; Wang, Le; Sorensen, Bryan K.; Tasker, Andrew S.; Sham, Hing; Shi-Chung, Ng; Cohen, Jerome; Devine, Edward; Cherian, Sajeev; Saeed, Badr; Zhang, Haichao; Jang Yun, Lee; Warner, Robert; Tahir, Stephen; Kovar, Peter; Ewing, Patricia; Alder, Jeffrey; Mitten, Michael; Leal, Juan; Marsh, Kennan; Bauch, Joy; Hoffman, Daniel J.; Sebti, Said M.; Rosenberg, Saul H. Journal of Medicinal Chemistry, 1999 , vol. 42, # 18 p. 3701 - 3710

~74%

N-benzylpyrazin-2-amine Structure

N-benzylpyrazin...

CAS#:7375-45-3

Literature: Martinez-Barrasa, Valentin; Delgado, Francisca; Burgos, Carolina; Luis Garcia-Navio; Luisa Izquierdo; Alvarez-Builla, Julio Tetrahedron, 2000 , vol. 56, # 16 p. 2481 - 2490

~%

N-benzylpyrazin-2-amine Structure

N-benzylpyrazin...

CAS#:7375-45-3

Literature: O'Connor, Stephen J.; Barr, Kenneth J.; Wang, Le; Sorensen, Bryan K.; Tasker, Andrew S.; Sham, Hing; Shi-Chung, Ng; Cohen, Jerome; Devine, Edward; Cherian, Sajeev; Saeed, Badr; Zhang, Haichao; Jang Yun, Lee; Warner, Robert; Tahir, Stephen; Kovar, Peter; Ewing, Patricia; Alder, Jeffrey; Mitten, Michael; Leal, Juan; Marsh, Kennan; Bauch, Joy; Hoffman, Daniel J.; Sebti, Said M.; Rosenberg, Saul H. Journal of Medicinal Chemistry, 1999 , vol. 42, # 18 p. 3701 - 3710

~%

N-benzylpyrazin-2-amine Structure

N-benzylpyrazin...

CAS#:7375-45-3

Literature: Duron, Sergio G.; Lindstrom, Andrew; Bonnefous, Celine; Zhang, Hui; Chen, Xiaohong; Symons, Kent T.; Sablad, Marciano; Rozenkrants, Natasha; Zhang, Yan; Wang, Li; Yazdani, Nahid; Shiau, Andrew K.; Noble, Stewart A.; Rix, Peter; Rao, Tadimeti S.; Hassig, Christian A.; Smith, Nicholas D. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 1237 - 1241

 N-benzylpyrazin-2-amineBioassay

View more

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Total 109, Current Page 1 of 11
1
2
3
4
5

 Synonyms

N-benzyl-N-(2-pyrazinyl)amine
benzyl-pyrazin-2-yl-amine
2-Benzylamino-pyrazin
N-benzyl-2-amino-1,4-pyrazine
Benzylamino-pyrazin
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.