Beta-Hydroxyisovalerylshikonin
Modify Date: 2024-01-11 19:14:50
Beta-Hydroxyisovalerylshikonin structure
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Common Name | Beta-Hydroxyisovalerylshikonin | ||
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| CAS Number | 7415-78-3 | Molecular Weight | 388.41100 | |
| Density | 1.312g/cm3 | Boiling Point | 616.9ºC at 760 mmHg | |
| Molecular Formula | C21H24O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 215.8ºC | |
Use of Beta-HydroxyisovalerylshikoninBeta-hydroxyisovalerylshikonin is a natural product isolated from Lithospermium radix, acts as a potent inhibitor of protein tyrosine kinases (PTK), with IC50s of 0.7μM and 1μM for EGFR and v-Src receptor, respectively. Beta-hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell-death in NCI-H522 and DMS114 cells[1]. |
| Name | β-HYDROXYISOVALERYLSHIKONIN |
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| Description | Beta-hydroxyisovalerylshikonin is a natural product isolated from Lithospermium radix, acts as a potent inhibitor of protein tyrosine kinases (PTK), with IC50s of 0.7μM and 1μM for EGFR and v-Src receptor, respectively. Beta-hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell-death in NCI-H522 and DMS114 cells[1]. |
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| Related Catalog | |
| Target |
IC50: 0.7 μM (EGFR), 1 μM (v-Src)[1] |
| References |
| Density | 1.312g/cm3 |
|---|---|
| Boiling Point | 616.9ºC at 760 mmHg |
| Molecular Formula | C21H24O7 |
| Molecular Weight | 388.41100 |
| Flash Point | 215.8ºC |
| Exact Mass | 388.15200 |
| PSA | 121.13000 |
| LogP | 2.83230 |
| Index of Refraction | 1.596 |