Nurr1 agonist 2

Modify Date: 2024-04-05 21:00:01

Nurr1 agonist 2 Structure
Nurr1 agonist 2 structure
Common Name Nurr1 agonist 2
CAS Number 742058-34-0 Molecular Weight 310.37
Density N/A Boiling Point N/A
Molecular Formula C18H14O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Nurr1 agonist 2


Nurr1 agonist 3 (Compound 7) is a Nurr1 agonist (EC50: 0.07 μM). Nurr1 agonist 3 binds to the recombinant Nurr1 ligand binding domain (LBD) with a Kd value of 0.14 μM. Nurr1 agonist 3 increases the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2) mRNA expression[1].

 Names

Name Nurr1 agonist 2

 Nurr1 agonist 2 Biological Activity

Description Nurr1 agonist 3 (Compound 7) is a Nurr1 agonist (EC50: 0.07 μM). Nurr1 agonist 3 binds to the recombinant Nurr1 ligand binding domain (LBD) with a Kd value of 0.14 μM. Nurr1 agonist 3 increases the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2) mRNA expression[1].
Related Catalog
References

[1]. Ballarotto M, et al.De Novo Design of Nurr1 Agonists via Fragment-Augmented Generative Deep Learning in Low-Data Regime. J Med Chem. 2023 Jun 22;66(12):8170-8177.  

 Chemical & Physical Properties

Molecular Formula C18H14O3S
Molecular Weight 310.37
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.