1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

Modify Date: 2024-01-04 13:16:31

1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid Structure
1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid structure
 Common Name 1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
CAS Number 74274-67-2 Molecular Weight 348.37200
Density 1.323g/cm3 Boiling Point 548.2ºC at 760 mmHg
Molecular Formula C17H21FN4O3 Melting Point N/A
MSDS N/A Flash Point 285.3ºC

 Names

Name 1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

 Chemical & Physical Properties

Density 1.323g/cm3
Boiling Point 548.2ºC at 760 mmHg
Molecular Formula C17H21FN4O3
Molecular Weight 348.37200
Flash Point 285.3ºC
Exact Mass 348.16000
PSA 78.67000
LogP 1.39850
Index of Refraction 1.585

 Synthetic Route

1-Ethylpiperazine structure

1-Ethylpiperazine

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7-chloro-1-ethyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid structure

7-chloro-1-ethy...

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~90%

1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid Structure

1-ethyl-7-(4-et...

CAS#:74274-67-2
Literature: Matsumoto; Miyamoto; Minamida; Nishimura; Egawa Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 292 - 301
1-ethyl-6-fluoro-1,4-dihydro-7-hydroxy-4-oxo-1,8-naphthyridine-3-carboxylic acid structure

1-ethyl-6-fluor...

CAS#:87939-09-1

~%

1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid Structure

1-ethyl-7-(4-et...

CAS#:74274-67-2
Literature: Matsumoto; Miyamoto; Minamida; Nishimura; Egawa Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 292 - 301
ethyl 7-(4-acetyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate structure

ethyl 7-(4-acet...

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~%

1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid Structure

1-ethyl-7-(4-et...

CAS#:74274-67-2
Literature: Matsumoto; Miyamoto; Minamida; Nishimura; Egawa Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 292 - 301
ethyl 7-(4-acetyl-1-piperazinyl)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate structure

ethyl 7-(4-acet...

CAS#:82671-13-4

~%

1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid Structure

1-ethyl-7-(4-et...

CAS#:74274-67-2
Literature: Matsumoto; Miyamoto; Minamida; Nishimura; Egawa Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 292 - 301
ethyl 7-chloro-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate structure

ethyl 7-chloro-...

CAS#:56654-05-8

~%

1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid Structure

1-ethyl-7-(4-et...

CAS#:74274-67-2
Literature: Matsumoto; Miyamoto; Minamida; Nishimura; Egawa Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 292 - 301
ethyl 7-(4-acetyl-1-piperazinyl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate structure

ethyl 7-(4-acet...

CAS#:54132-41-1

~%

1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid Structure

1-ethyl-7-(4-et...

CAS#:74274-67-2
Literature: Matsumoto; Miyamoto; Minamida; Nishimura; Egawa Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 292 - 301
ethyl 7-(4-acetylpiperazin-1-yl)-6-amino-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate structure

ethyl 7-(4-acet...

CAS#:87938-96-3

~%

1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid Structure

1-ethyl-7-(4-et...

CAS#:74274-67-2
Literature: Matsumoto; Miyamoto; Minamida; Nishimura; Egawa Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 292 - 301
ethyl 7-(4-acetylpiperazin-1-yl)-1-ethyl-6-nitro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate structure

ethyl 7-(4-acet...

CAS#:87939-04-6

~%

1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid Structure

1-ethyl-7-(4-et...

CAS#:74274-67-2
Literature: Matsumoto; Miyamoto; Minamida; Nishimura; Egawa Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 292 - 301
hexafluoro-l6-phosphane, 2-(4-acetylpiperazin-1-yl)-6-(ethoxycarbonyl)-8-ethyl-5-oxo-5,8-dihydro-1,8-naphthyridine-3-diazonium salt structure

hexafluoro-l6-p...

CAS#:87938-98-5

~%

1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid Structure

1-ethyl-7-(4-et...

CAS#:74274-67-2
Literature: Matsumoto; Miyamoto; Minamida; Nishimura; Egawa Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 292 - 301
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Chemsrc provides CAS#:74274-67-2 MSDS, density, melting point, boiling point, structure, etc. Its name is 1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid>> amp version: 1-ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

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