2-Methoxy-5H-pyrido(3,2:5,6)(1,4)thiazino(2,3-b)quinoxaline

Modify Date: 2025-09-18 12:46:44

2-Methoxy-5H-pyrido(3,2:5,6)(1,4)thiazino(2,3-b)quinoxaline Structure
2-Methoxy-5H-pyrido(3,2:5,6)(1,4)thiazino(2,3-b)quinoxaline structure
Common Name 2-Methoxy-5H-pyrido(3,2:5,6)(1,4)thiazino(2,3-b)quinoxaline
CAS Number 74396-45-5 Molecular Weight 282.32000
Density 1.416g/cm3 Boiling Point 526.2ºC at 760 mmHg
Molecular Formula C14H10N4OS Melting Point N/A
MSDS N/A Flash Point 272ºC

 Names

Name 7-Methoxy-1,4,6-benzotriazaphenothiazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.416g/cm3
Boiling Point 526.2ºC at 760 mmHg
Molecular Formula C14H10N4OS
Molecular Weight 282.32000
Flash Point 272ºC
Exact Mass 282.05800
PSA 85.23000
LogP 3.37960
Index of Refraction 1.728
InChIKey LQIKBHOZELDRRD-UHFFFAOYSA-N
SMILES COc1ccc2c(n1)Sc1nc3ccccc3nc1N2

 Synthetic Route

~91%

2-Methoxy-5H-pyrido(3,2:5,6)(1,4)thiazino(2,3-b)quinoxaline Structure

2-Methoxy-5H-py...

CAS#:74396-45-5

Literature: Okafor Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 1 p. 149 - 153

~%

2-Methoxy-5H-pyrido(3,2:5,6)(1,4)thiazino(2,3-b)quinoxaline Structure

2-Methoxy-5H-py...

CAS#:74396-45-5

Literature: Okafor Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 1 p. 149 - 153

~%

2-Methoxy-5H-pyrido(3,2:5,6)(1,4)thiazino(2,3-b)quinoxaline Structure

2-Methoxy-5H-py...

CAS#:74396-45-5

Literature: Okafor Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 1 p. 149 - 153

~%

2-Methoxy-5H-pyrido(3,2:5,6)(1,4)thiazino(2,3-b)quinoxaline Structure

2-Methoxy-5H-py...

CAS#:74396-45-5

Literature: Okafor Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 1 p. 149 - 153

 Bioassay

View more

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
Source: ChEMBL
Target: Klebsiella pneumoniae
External Id: CHEMBL4296186
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Identifying Sarm1 TIR NADase inhibitors through high throughput HPLC assay
Source: 24386
Target: N/A
External Id: Sarm1 TIR NADase inhibitors
Name: Fluorescence polarization-based biochemical high throughput confirmation assay to ide...
Source: The Scripps Research Institute Molecular Screening Center
Target: abhydrolase domain-containing protein 4 isoform 1 [Mus musculus]
External Id: ABHD4_INH_FP_1536_3X%INH CRUN
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 Synonyms

2-Methoxy-5H-pyrido(3',2':5,6)(1,4)thiazino(2,3-b)quinoxaline
7-Methoxy-1,4,6-benzo[b]triazaphenothiazine
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