Dideoxycytidinene

Modify Date: 2025-08-27 10:18:56

Dideoxycytidinene structure	Common Name	Dideoxycytidinene
	CAS Number	7481-88-1	Molecular Weight	209.20
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₁₁N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dideoxycytidinene

Dideoxycytidinene (2′,3′-Didehydro-2′,3′-dideoxycytidine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	Dideoxycytidinene

Description	Dideoxycytidinene (2′,3′-Didehydro-2′,3′-dideoxycytidine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₉H₁₁N₃O₃
Molecular Weight	209.20
Exact Mass	209.08000
PSA	90.37000
InChIKey	OOBICGOWICFMIX-POYBYMJQSA-N
SMILES	Nc1ccn(C2C=CC(CO)O2)c(=O)n1

RIDADR	NONH for all modes of transport

N4-acetyl-2',3'...

CAS#:119794-43-3

~70%

Dideoxycytidinene

CAS#:7481-88-1

Literature: Chu; Bhadti; Doboszewski; Gu; Kosugi; Pullaiah; Van Roey Journal of Organic Chemistry, 1989 , vol. 54, # 9 p. 2217 - 2225

N4-acetyl-5'-O-...

CAS#:119794-42-2

Dideoxycytidinene

CAS#:7481-88-1

Literature: Chu; Bhadti; Doboszewski; Gu; Kosugi; Pullaiah; Van Roey Journal of Organic Chemistry, 1989 , vol. 54, # 9 p. 2217 - 2225

Precursor 2
CAS#:119794-43-3 N4-acetyl-2',3'... CAS#:119794-42-2 N4-acetyl-5'-O-...
DownStream 1
CAS#:7481-89-2 Zalcitabine

Name: Cytotoxicity against human peripheral blood mononuclear cells (PBMC)
Source: ChEMBL
Target: N/A
External Id: CHEMBL757721

Name: Protection of ATH8 cells against the cytopathic effect of HIV.
Source: ChEMBL
Target: ATH-8 cell line
External Id: CHEMBL645707

Name: Required dose to reduce viability of normal uninfected ATH8 cells.
Source: ChEMBL
Target: ATH-8 cell line
External Id: CHEMBL645708

Name: Toxicity was determined by evaluation of cluster morphology and reclustering properti...
Source: ChEMBL
Target: MT4
External Id: CHEMBL713147

Name: Effective concentration against HIV-1 in human peripheral blood mononuclear cells (PB...
Source: ChEMBL
Target: Human immunodeficiency virus 1
External Id: CHEMBL696654

Name: Stability of the compound at pH 1 assessed as half-life
Source: ChEMBL
Target: N/A
External Id: CHEMBL5247120

Name: Toxicity was determined by evaluation of cluster morphology and reclustering properti...
Source: ChEMBL
Target: MT4
External Id: CHEMBL713149

Name: Partition coefficient (P) in 1-octanol and 0.1 M Na3PO4 at pH 7
Source: ChEMBL
Target: N/A
External Id: CHEMBL630739

Name: Toxicity was determined by evaluation of cluster morphology and reclustering properti...
Source: ChEMBL
Target: MT4
External Id: CHEMBL713151

Name: HIV Enzyme Data
Source: NIAID
Target: N/A
External Id: HIV Enzyme Data

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Dideoxycytidinene

Use of Dideoxycytidinene

Names

Dideoxycytidinene Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Precursor & DownStream

DideoxycytidineneBioassay

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.