4,6-dichloro-2-methyl-5-(1-acetyl-2-imidazolin-2-yl)-aminopyridine

Modify Date: 2026-07-15 09:21:31

4,6-dichloro-2-methyl-5-(1-acetyl-2-imidazolin-2-yl)-aminopyridine Structure
4,6-dichloro-2-methyl-5-(1-acetyl-2-imidazolin-2-yl)-aminopyridine structure
Common Name 4,6-dichloro-2-methyl-5-(1-acetyl-2-imidazolin-2-yl)-aminopyridine
CAS Number 75438-54-9 Molecular Weight 288.13
Density 1.5±0.1 g/cm3 Boiling Point 390.4±52.0 °C at 760 mmHg
Molecular Formula C10H11Cl2N5O Melting Point N/A
MSDS N/A Flash Point 189.9±30.7 °C

 Names

Name 4,6-dichloro-2-methyl-5-(1-acetyl-2-imidazolin-2-yl)-aminopyridine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 390.4±52.0 °C at 760 mmHg
Molecular Formula C10H11Cl2N5O
Molecular Weight 288.13
Flash Point 189.9±30.7 °C
Exact Mass 287.0340654
PSA 57.59000
LogP 0.22
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.662
InChIKey UPSZQCBUTUCGAR-UHFFFAOYSA-N
SMILES CC1=NC(=C(C(=N1)Cl)NC2=NCCN2C(=O)C)Cl

 Safety Information

HS Code 2933990090

 Synthetic Route

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4,6-dichloro-2-methyl-5-(1-acetyl-2-imidazolin-2-yl)-aminopyridine Structure

4,6-dichloro-2-...

CAS#:75438-54-9

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Literature: EP2586779 A1, ; Paragraph 0036 ;

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4,6-dichloro-2-methyl-5-(1-acetyl-2-imidazolin-2-yl)-aminopyridine Structure

4,6-dichloro-2-...

CAS#:75438-54-9

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Literature: WO2008/73125 A1, ; Page/Page column 12-13 ;

~%

4,6-dichloro-2-methyl-5-(1-acetyl-2-imidazolin-2-yl)-aminopyridine Structure

4,6-dichloro-2-...

CAS#:75438-54-9

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Literature: WO2008/73125 A1, ; Page/Page column 12-13 ;

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Bioassay

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Name: NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in...
Source: ChEMBL
Target: Plasmodium falciparum
External Id: CHEMBL1040691
Name: Inhibitors of CDC25B-CDK2/CyclinA interaction
Source: Center for Chemical Genomics, University of Michigan
External Id: MScreen:TargetID_600
Name: NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compoun...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1040694
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN
Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
Name: NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in er...
Source: ChEMBL
Target: Plasmodium falciparum
External Id: CHEMBL1040692
Name: NOVARTIS: Antimalarial liver stage activity measured as a greater than 50% reduction ...
Source: ChEMBL
Target: Plasmodium yoelii
External Id: CHEMBL1789905
Name: NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
Source: ChEMBL
Target: Huh-7
External Id: CHEMBL1040693
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 Synonyms

1-{2-[(2,4-Dichloro-6-methyl-3-pyridinyl)amino]-4,5-dihydro-1H-imidazol-1-yl}ethanone
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